Selenium(Se)is an essential micronutrient for human body that plays an important physiological function in life.Compared with inorganic selenium,organic selenium has high bioavailability and low toxicity,making it a superior source of selenium supplementation.Bioactive selenium-containing peptides are important forms of organic selenium,mainly be isolated from selenium-enriched plants and obtained from synthetic pathway,which have become a research hotspot in recent years due to their multiple healthful biological activities.In this review,the isolation and artificial chelating preparation,and the common sources of plant-derived bioactive selenium-containing peptides,as well as their various bioactivities such as antioxidant,hepatoprotective,immunomodulatory,anticancer,hypotensive are summarized.This review would provide a theoretical reference for the development and utilization of plant-derived bioactive selenium-containing peptides in functional foods and medicines.
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