Ion mobility spectroscopy is a technique to characterize compounds based on the differences in the migration of sample ions under the combined action of electric field and air flow.Ions can be separated according to their quantity of electric charge,mass,size and shape.Meanwhile,the collision cross section of the ions can also be calculated to obtain chemical compound structural information,which has shown excellent performance in separating isomers of substances.In recent years,a variety of ion mobility technologies combined with mass spectrometry technology have emerged,and been widely used in food,biology,medicine,environment and other fields.In this paper,the types and working principles of ion mobility spectroscopy are introduced,the advantages and disadvantages of various types of instruments are analyzed,and the application of ion mobility spectrometry,liquid chromatography and mass spectrometry multidimensional combination in analyzing and identifying nutritive and active ingredients and chemical hazards in food is reviewed.The application prospect and development trend of this technology are also prospected.
关键词
离子淌度谱(IMS)/离子淌度质谱(IM-MS)/碰撞横截面积(CCS)/营养活性成分/化学危害物
Key words
ion mobility spectrometry(IMS)/ion mobility mass spectrometry(IM-MS)/collision cross section(CCS)/nutrient and active ingredients/chemical hazards
维普
万方数据