Stoichiometry Analysis on Inhibition of α-Glycosidase Activity of Citrus Peel
Objective:To incestigate the inhibitory activity of Citrus peel against α-glycosidase.Methods:High-performance liquid chromatography(HPLC)was used to determine the content of seven flavonoid components in 13 batches of Citrus peel,establishing a fingerprint.Chemometric methods including cluster analysis,principle component analysis,partial least squares discriminant analysis(PLS-DA),were employed to analyze the spectrum effect relationship between Citrus peel and enzyme inhibition.Results:All 13 batches of Citrus peel had better α-glycosidase inhibition and contained flavonoid components such as naringin,hesperidin,neohesperidin,hespididin,sweet orange flavone,nobiletin and hesperetin.The stoichiometric results showed that hesperetin was the main component of α-glycosidase inhibitory activity in Citrus peel.Conclusion:Citrus peel from Citrus plants can be used in the development of health products for hypoglycemia.
万方数据
维普
