A Review of Matrix Effects in Pesticide Residue Detection
Pesticide residue detection is an important task in ensuring food safety.Gas chromatography-tandem mass spectrometry(GC-MS/MS)and liquid chromotography-tandem mass spectrometry(LC-MS/MS)are widely used for pesticide residue detection due to their high accuracy.However,matrix effects can affect the accuracy of the detection results.In order to ensure the accuracy and reliability of pesticide residue analysis results,it is necessary to evaluate and mitigate or compensate for matrix effects.The main factors affecting matrix effects include pesticide properties and structures,pesticide concentrations,matrix types,types of detection instruments,and chromatographic and mass spectrometric conditions.Measures to compensate for matrix effects include direct dilution method,internal standard method,analysis protector method,matrix-matching standard solution correction method,matrix purification method,standard addition method,and representative matrix compensation method.The paper reviews the definition and formation mechanisms of matrix effects,evaluation methods,factors influencing matrix effects,and compensation strategies,aiming to provide insights into addressing the uncertainties caused by matrix effects in pesticide residue detection.
pesticide residuematrix effectgas chromatography-tandem mass spectrometryliquid chromotography-tandem mass spectrometry