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纤细裸藻中副淀粉与脂质代谢研究进展

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纤细裸藻(Euglena gracilis)不仅是一种具有高附加值的保健食品,其胞内的副淀粉在生物医药领域具有潜在的应用价值.近年来,随着对纤细裸藻的深入研究,关于其在异养发酵、副淀粉的结构分析及生理功效等方面均取得了很大的成果,但是关于其副淀粉与脂质代谢与调控的综述报道较少.文章对纤细裸藻副淀粉与脂质代谢方面进行了综述,包括副淀粉合成与代谢途径、蜡酯的生物合成途径,以及营养限制、外源添加剂、光照等不同环境条件对纤细裸藻副淀粉与脂质积累的影响.此外,还总结了利用代谢组学揭示纤细裸藻在不同条件下副淀粉代谢中的关键代谢物及调控因子方面的研究进展,并对限制进一步研究纤细裸藻副淀粉及脂质代谢的问题以及未来可能的研究方向进行了展望,旨在为纤细裸藻代谢发酵的基础研究提供参考.
Research Progress on Paramylon and Lipid Metabolism in Euglena gacilis
Euglena gracilis is not only a kind of health food with high added value,but its intracellular paramylon has potential application value in the field of biomedicine.In recent years,with the in-depth study of E.gracilis,great achievements have been made in heterotrophic fermentation,structural analysis and physiological effects of paramylon.However the studies on paramylon and lipid metabolism and regulation of E.gracilis have been rarely reviewed.This article reviews the paramylon and lipid metabolism of E.gracilis,including the synthesis and degradation pathways of paramylon and the biosynthesis pathways of wax ester,as well as the effects of different environmental conditions such as nutrient limitation,exogenous additives and light on the accumulation of paramylon and lipid in E.gracilis.Moreover,it summarized the research progress on using metabolomics to reveal the key metabolites and regulatory factors in the metabolism of paramylon in E.gracilis under different conditions.The problems restricting further research on the metabolism of paramylon and lipid in E.gracilis and the possible future research directions are prospected.The aim is to provide a reference for the basic research on fermentation of E.gracilis.

Euglena gracilisparamylonmetabolismmetabolomics

廖金燕、郑明敏

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福建师范大学生命科学学院,福建 福州 350117

福建师范大学工业微生物教育部工程研究中心,福建 福州 350117

纤细裸藻 副淀粉 代谢 代谢组学

2024

食品科技
北京市粮食科学研究所

食品科技

CSTPCD北大核心
影响因子:0.622
ISSN:1005-9989
年,卷(期):2024.49(8)