An Experimental Animal Investigation on Toxicity and Blood Lipid Modulating Effect of Kadsura coccinea Fruit
The aim of this study was to investigate the toxicity and blood lipid modulating effect of ripe Kadsura conccinea fruit in vivo by maximal tolerance dose (MTD) test and 30-d feeding test in mice. Blood lipid changes in mice were analyzed during 30 days of Kadsura conccinea fruit feeding. The results showed MTD was ＞ 20 mL/kg for both male and female mice, indicating that Kadsura conccinea fruit was non-toxic. Kadsura conccinea fruit had significant effect on neither mouse weight nor viscera but could obviously reduce the level of cholesterol in mouse blood. Thus, it can be considered that ripe Kadsura conccinea fruit deserves to be exploited as a rare wild fruit with the benefits of non-toxicity and modulating blood lipids.
国家科技期刊平台
NSTL
万方数据
维普
