Progress in Research on Biofilm Formation Regulated by LuxS/AI-2 Quorum Sensing
Themajority of bacteriaform biofilms for growth and development and bacteria within biofilms may better adapt to environment than their planktonic counterparts. LuxS-dependent quorum sensing is a widespread system used by bacteria for cell-to-cell communication, which can regulate biofilm formation in a cell density-dependent manner. Autoinducer 2 (AI-2) produced by LuxS, is a species-nonspecific signal used by both gram-negative and gram-positive bacteria for biofilm formation. Currently, several inhibitors of LuxS/AI-2 quorum sensing have been determined to influence biofilm formation based on their anti-AI-2 communication mechanisms. Recently, there has been a surging interest in the mechanism of biofilm regulation by LuxS/AI-2 quorum sensing system, which is important to better understand the relationship between LuxS-dependent QS system and biofilm formation.
biofilmsLuxS/AI-2 quorum sensingautoinducer 2quorum sensing inhibitorregulation mechanism
国家科技期刊平台
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万方数据
维普
