首页|基于质谱的脂质C=C和脂肪酰基位置鉴定方法及其在食品分析中的应用研究进展

基于质谱的脂质C=C和脂肪酰基位置鉴定方法及其在食品分析中的应用研究进展

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脂质在生命体中发挥着重要作用,结构影响功能,脂质精细结构解析至关重要。但脂质结构的多样性和相似性对脂质分析提出了巨大挑战。质谱是脂质分析的重要技术之一,在脂质C=C和脂肪酰基位置结构解析中有着较好的应用。本文介绍脂质分析的前处理方法,综述基于质谱的C=C位置和脂肪酰基位置鉴定方法,并讨论该方法在食品分析中的应用,最后展望质谱在脂质化合物精确结构解析方面的发展趋势,以期为不饱和脂质C=C位置和脂肪酰基位置鉴定以及异构体识别和定量分析技术发展和应用提供参考。
An Update on Mass Spectrometry-Based Methods for the Identification of Lipid C=C and Fatty Acyl Positions and Their Applications in Food Analysis
Lipids play an important role in living organisms,and the structure affects the function.Analysis of the fine structure of lipids is very important.However,the diversity and similarity of lipid structures pose a great challenge for lipid analysis.Mass spectrometry(MS)is one of the important methods for lipid analysis,and it has a good application in the structural elucidation of lipid C=C and fatty acyl positions.In this article,the pretreatment methods for lipid analysis are introduced,and the MS-based methods for the identification of C=C and fatty acyl positions in lipids are reviewed.Additionally,the applications of these methods in food analysis are discussed.Finally,this review presents an outlook on future trends in the development of MS in the accurate structure elucidation of lipid compounds in order to provide a reference for the identification and quantitative analysis of C=C and fatty acyl positions and their isomers in unsaturated lipids.

lipidsmass spectrometryC=C positionfatty acyl positionapplication

滕蒙南、段晓亮、张东、郭伟群

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浙江农林大学食品与健康学院,浙江 杭州 311302

国家粮食和物资储备局科学研究院,北京 102629

脂质 质谱 C=C位置 脂肪酰基位置 应用

2025

食品科学
北京食品科学研究院

食品科学

北大核心
影响因子:1.327
ISSN:1002-6630
年,卷(期):2025.46(1)