Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans
Moderate intake of whole grains and non-soy legumes can improve glucose and lipid metabolism,but excessive intake may have an adverse effect.Due to the lack of corresponding conversion relationships,the intake of whole grains and non-soy legumes in mouse feed cannot directly serve as a reference for human intake.This paper introduces the addition levels of common whole grains and non-soy legumes in mouse feed and explores their relationship with the recommended dietary intakes(RDI)of common whole grains and non-soy legumes in humans using various methods,including equivalent coefficient,surface area ratio,body shape coefficient,food density,body surface area index,energy conversion,and nutrient conversion methods.The results indicate that the RDI of 50-150 g of whole grains and non-soy legumes in humans could be equivalently converted into addition of 5%-50%whole grains and beans in the feed of mice with a 3 g daily feed intake.Dietary addition of whole grains and non-soy legumes exceeding 50%might place mice at risk for overconsumption.This study provides an important reference for establishing the conversion relationship between the amounts of whole grains and non-soy legumes added to mouse feed and the RDI of whole grains and non-soy legumes in humans.
dose conversionwhole grainsnon-soy legumesbody surface area