首页|蓝莓花青素对糖尿病小鼠器官抗氧化能力的研究

蓝莓花青素对糖尿病小鼠器官抗氧化能力的研究

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为研究蓝莓花青素对糖尿病小鼠肝、肾、心脏组织的抗氧化能力的影响,以腹腔注射链脲佐菌素,成功制得糖尿病小鼠模型后进行分组.连续给药4周后,测定各组小鼠肝脏、肾脏、心脏组织中的丙二醛含量,超氧化物歧化酶、谷胱甘肽过氧化物酶活力,总抗氧化能力以及抑制羟基自由基能力.结果表明:在小鼠器官组织中,模型十剂量组与模型对照组相比,丙二醛含量显著降低(P<0.05),谷胱甘肽过氧化物酶、超氧化物歧化酶活性、总抗氧化能力和抑制羟自由基能力显著增加(P<0.05),表明蓝莓花青素能保护受损的器官,具有一定的抗氧化作用.
Effects of blueberry anthocyanin on organ tissue antioxidant defense function in experimental diabetic mice
To study the effects of blueberry anthocyanin on organ tissue antioxidant activity in experimental diabetic mice.The instrep-tozotocin-induced diabetic mice were divided into different groups.Diabetic mice were administered for 4 weeks,Malondialdehyde content,the activity of superoxide dismutase and glutathione peroxides,total antioxidant capacity,inhibiting ability of hydroxyl radicals on organ tissue were determined.The experimental data showed that model with blueberry anthocyanin group compared with model control,the content of Malondialdehyde were significantly reduced (P<0.05) while glutathione peroxidase,superoxide dismutase and total antioxidant capacity,inhibiting hydroxyl free radical ability increased markedly in the tissue of all organ (P<0.05).It shows that Blueberry anthocyanin can enhance the cell tissue antioxidant activity.

blueberryanthocyanin diabetic miceantioxidant activity

韦艳双、田密霞、张美娇、袁烽皓

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大连民族大学,辽宁大连116600

蓝莓 花青素 糖尿病小鼠 抗氧化能力

大连民族大学自主青年基金大连民族学院“大学生创新创业训练计划”项目

DC201501082X201503055

2016

食品与机械
长沙理工大学

食品与机械

CSTPCDCSCD北大核心
影响因子:0.89
ISSN:1003-5788
年,卷(期):2016.32(6)
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