Objective:This study aimed to evaluate the determination uncertainty of four quinolones residues in honey by liquid chromatography-tandem mass spectrometry(LC-MS/MS).Methods:Based on GB 31657.2-2021,a mathematical model for sources of uncertainty evaluation was established.The uncertainty of each variable which affect the result were calculated and the weight of each uncertainty component was assessed.Results:The uncertainties in the determination of enrofloxacin,sarafloxacin,ofloxacin and ciprofloxacin in honey were(4.97±0.81),(10.13±1.58),(7.67±1.23),(14.97± 2.25)μg/kg(P=95％,k=2)respectively.Conclusion:The main influencing factors of the determination uncertainty were preparation and dilution process of standard solution and fitting of standard curve,which should be controlled in practical work.
关键词
不确定度/液相色谱—串联质谱法/恩诺沙星/沙拉沙星/氧氟沙星/环丙沙星/蜂蜜
Key words
uncertainty/liquid chromatography-tandem mass spectrometry(LC-MS/MS)/enrofloxacin/sarafloxacin/ofloxacin/ciprofloxacin/honey
维普
万方数据