Antimicrobial peptide-coupled silver nanomaterials and their applications in medical and food fields
Due to antimicrobial activity,nanoparticles(NPs)in combination with antimicrobial peptides(AMPs)can be used to kill drug-resistant(MDR)pathogens.Nanosilver(AgNPs)has broad-spectrum and efficient antimicrobial properties,multiple bacterial inactivation mechanisms,and the ability to fine-tune the conjugation on the surface of antimicrobial peptide-conjugated silver nanoparticles(AMP-AgNPs),which results in higher biosafety of AMP-AgNPs.The review summarized the latest research progress of AMP-AgNPs conjugates and discussed the synthesis method,antibacterial activity,mechanism of action,hemolytic toxicity of AMP-AgNPs conjugates,as well as their applications in medical and food fields.The future development direction of AMP-AgNPs conjugates was also prospected.
国家科技期刊平台
NSTL
万方数据
