Effect of home enteral nutrition on postoperative patients with esophageal cancer
Objective To explore the effects of home enteral nutrition on liver and kidney function,serum nutritional inde-xes and nutritional tolerance in patients with esophageal cancer.Methods A total of 105 postoperative patients with e-sophageal cancer treated in the First Affiliated Hospital of Henan University of Science and Technology from 2020-09-07 to 2022-12-23 were selected as the study objects,and were divided into non-enteral nutrition group and enteral nutrition group according to nutritional intervention methods.After discharge,52 patients in the non-enteral nutrition group were given non-home enteral nutrition,and 53 patients in the enteral nutrition group were given home enteral nutrition.Liver and kidney function,nutritional indexes,nutritional tolerance and malnutrition were compared between the two groups.The normally distributed continuous data within the groups were analyzed using one-way ANCOVA before intervention and at 2 months after discharge,and the count data were tested using the Fisher's exact probability method.Results Uni-variate covariance analysis showed that the alanine aminotransferase(ALT)level of the enteral nutrition group was(37.15±10.48)U/L after discharge 2 months,which was higher than that of the non-enteral nutrition group(34.21± 8.23)U/L,and the difference was statistically significant,F=24.846,P＜0.001.The blood urea nitrogen(BUN)level was(5.35±1.72)μmol/L,higher than that of non-enteral nutrition group(4.97±1.26)μmol/L,and the difference was statistically significant(F=5.747,P=0.018).The level of aspartate transferase(AST)was(32.17±8.24)U/L,higher than that of non-enteral nutrition group(29.83±6.17)U/L,but the difference was not statistically significant(F=1.547,P=0.217).Serum creatinine(Scr)level was(73.16±13.75)μmol/L,higher than that of non-enteral nu-trition group(71.36±9.82)μmol/L,but the difference was not statistically significant(F=1.475,P=0.227).The body mass index(BMI)level of the enteral nutrition group was(23.64±1.28)kg/m2 2 months after discharge,which was higher than that of the non-enteral nutrition group(21.73±1.45)kg/m2,and the difference was statistically signifi-cant,F=124.080,P＜0.001.Hemoglobin(Hb)level was(128.13±7.68)g/L,higher than that of non-enteral nutri-tion group(120.43±9.15)g/L,the difference was statistically significant,F=824.701,P＜0.001.Albumin(ALB)level was(48.61±9.12)g/L,higher than that of non-enteral nutrition group(42.11±8.24)g/L,and the difference was statistically significant(F=4 63.774,P＜0.001).According to Fisher's exact probability test,the nutritional intol-erance rate in the enteral nutrition group was 1.89％(1/53),compared with 5.77％(3/52)in the non-enteral nutrition group,the difference was not statistically significant(P=0.363).The incidence of malnutrition in the enteral nutrition group was 0,and the difference was not statistically significant compared with the non-enteral nutrition group 5.77％(3/52),P=0.118.Conclusion Home enteral nutrition can improve serum nutritional indexes,regulate liver and kidney function,and have good nutritional tolerance and no malnutrition events.
home enteral nutritionesophageal cancerliver and kidney functionnutritional tolerancemalnutrition
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