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甘油三酯/胱抑素C比值对2型糖尿病患者并发症的诊断效果

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目的 分析甘油三酯/胱抑素C(TG/Cys-C)比值对2型糖尿病患者并发症的诊断效果.方法 回顾性分析2021-01-01-2022-01-01郑州市第一人民医院收治的167例2型糖尿病(T2DM)患者的临床资料,依据其是否发生并发症分为并发症组(n=126)和对照组(n=41),比较2组的各项资料,对差异统计学有意义的因素进一步行logistic多因素分析,明确T2DM患者发生并发症的危险因素,并分析各危险因素对T2DM患者并发症的诊断效果.结果 并发症组患者收缩压(160.23±14.20)mmHg、舒张压(91.12±10.36)mmHg、糖尿病病程(84.52±19.65)月、空腹血糖(7.65±1.02)mmol/L、胱抑素 C(1.47±0.26)mg/L、肌酐(110.56±16.37)μmol/L 水平均高于对照组的收缩压(134.65±20.62)mmHg、舒张压(81.14±9.56)mmHg、糖尿病病程(13.16±3.42)月、空腹血糖(7.10±1.17)mmol/L、胱抑素 C(0.85±0.19)mg/L、肌酐(69.56±17.84)μmol/L水平,高血压占比(84.13%)高于对照组(60.98%),血红蛋白(113.52±23.36)g/L、尿酸(328.56±74.51)μmol/L、TG/Cys-C 比值(1.23±0.32)水平均低于对照组的血红蛋白(136.56±20.74)g/L、尿酸(368.65±59.45)μmol/L、TG/Cys-C 比值(2.82±0.44)水平,差异统计学有意义,均 P<0.05.高血压、糖尿病病程、TG/Cys-C比值为T2DM患者发生并发症的危险因素,P<0.05.收缩压(95%CI为1.064~3.780)、糖尿病病程(95%CI 为 1.054~1.196)、TG/Cys-C 比值(95%CI 为 0.271~0.670)单项检测对于 T2DM 患者并发症均有一定诊断价值,但三者联合应用诊断效果更佳.结论 高血压、糖尿病病程、TG/Cys-C比值为T2DM患者发生并发症的危险因素,三者单项检测对于T2DM患者并发症均有一定诊断价值,但三者联合应用诊断效果更佳.
The diagnostic effect of triglyceride/cystatin C ratio on complications of type 2 diabetes patients
Objective To analyze the diagnostic effect of triglyceride/cystatin C ratio(TG/Cys-C)on the complications of type 2 diabetes patients.Methods The clinical data of 167 patients with type 2 diabetes(T2DM)admitted to the First People's Hospital of Zhengzhou City from January 1,2021 to January 1,2022 were retrospectively analyzed.They were di-vided into a complication group(n=126)and a control group(n=41)based on whether they had complications.The data of the two groups were compared,and the factors with statistically significant difference were further analyzed using logis-tic multifactor analysis to identify the risk factors of complications in T2DM patients.The diagnostic effect of various risk factors on complications in T2 DM patients was analyzed.Results Patients in the complication group had higher systolic blood pressure(160.23±14.20)mmHg,diastolic blood pressure(91.12±10.36)mmHg,duration of diabetes(84.52±19.65)months,fasting blood glucose(7.65±1.02)mmol/L,cystatin C(1.47±0.26)mg/L,creatinine(110.56±16.37)μmol/L than the control group's systolic blood pressure(134.65±20.62)mmHg,diastolic blood pressure(81.14±9.56)mmHg,duration of diabetes(13.16±3.42)months,fasting blood glucose(7.10±1.17)mmol/L,cystatin C(0.85±0.19)mg/L,creatinine(69.56±17.84)μmol/L.The proportion of hypertension(84.13%)was higher than that of the control group(60.98%),and the levels of hemoglobin(113.52±23.36)g/L,uric acid(328.56±74.51)μmol/L,and TG/Cys-C ratio(1.23±0.32)were lower than those of the control group's hemoglobin(136.56±20.74)g/L,uric acid(368.65±59.45)μmol/L,and TG/Cys-C ratio(2.82±0.44).hese differences were statistically significant,with all P<0.05.Hypertension,the course of diabetes and TG/Cys-C ratio were the risk factors for complications in T2DM pa-tients(P<0.05).Systolic blood pressure(95%CI:1.064-3.780),duration of diabetes(95%CI:1.054-1.196),and TG/Cys-C ratio(95%CI:0.271-0.670)have certain diagnostic value for the complications of T2DM patients,but the combina-tion of the three has better diagnostic effect.Conclusions Hypertension,duration of diabetes,and TG/Cys-C ratio are risk factors for complications in T2 DM patients.The single detection of these three factors has certain diagnostic value for complications in T2 DM patients,but the combined application of these three factors is more effective.

type 2 diabetescomplicationrisk factorstriglyceride/cystatin C ratiodiagnosis

康曼琳、袁世琪、王旭昕

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郑州市第一人民医院检验科,河南郑州 450000

2型糖尿病 并发症 危险因素 甘油三酯/胱抑素C比值 诊断

2024

社区医学杂志
中华预防医学会

社区医学杂志

影响因子:0.588
ISSN:1672-4208
年,卷(期):2024.22(11)