Epidemiological characteristics and trend of liver cancer mortality in Zhaoyuan city,Shandong from 1985 to 2023
Objective To analyze the changes of liver cancer mortality rate in Zhaoyuan from 1985 to 2023,and provide a basis for the prevention and control of liver cancer.Methods Based on the monitoring data of all causes of death in Zhaoyuan City,liver cancer mortality data from 1985 to 2023 were extracted.Excel 2010 and SAS9.3 were used to calcu-late the crude mortality rates,standardized rates,cumulative rates and truncated rates;Joinpoint5.0 software was used to perform regression analysis on the age-standardized liver cancer mortality rates from 1985 to 2023,and the annual change percentage(APC)was calculated.The contribution of population factors and non-population factors was calculated by de-composing the differences in mortality rates.Results Totally 9 080 deaths of liver cancer were reported in Zhaoyuan city from 2008 to 2023.The crude mortality rate was 42.31/105,ranking third among malignant tumors following gastric cancer and lung cancer.The age-standardized mortality rate was 21.30/105 and the world-standardized rate was 28.03/105;The mortality rate of liver cancer showed an upward trend with increasing age.,The age-standardized mortality rate AAPC was-0.95,P>0.05.The standardized rate increased from 1985 to 1998,with an APC of 4.00,and decreaseed from 1998 to 2023,with an APC of-3.43,P<0.05.Population factors have always been a factor contributing to the increase in liver cancer mortality,and their role has become increasingly evident..non-demographic factors reached its maximum effect from 1995 to 1999,and then began to weaken,resulting the decrease in mortality rate from 2010 to 2023.Conclusions Although the mortality rate of liver cancer in Zhaoyuan City has shown a downward trend,it remains at a relatively high level and is a significant cancer that seriously endangers the health of Zhaoyuan residents.Early diag-nosis and early treatment is suggested to reduce the mortality of liver cancer in Zhaoyuan City.