首页|山东省招远市1985-2023年肝癌死亡流行特征及趋势分析

山东省招远市1985-2023年肝癌死亡流行特征及趋势分析

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目的 分析招远市1985-2023年肝癌死亡率变化情况,为肝癌防控提供依据.方法 基于招远市全死因监测数据,提取1985-2023年肝癌死亡资料.采用Excel 2010和SAS9.3软件计算粗死亡率、标化率、累积率、截缩率;采用Joinpoint5.0软件对1985-2023年肝癌的中标率进行回归分析,计算年度变化百分率(APC).采用死亡率的差别分解计算人口因素和非人口因素的贡献.结果 招远市1985-2023年共计死亡9 080例,粗死亡率为42.31/10万,仅次于胃癌、肺癌,为恶性肿瘤死亡顺位第3位.中标率为21.30/10万,世标率为28.03/10万;随着年龄的增加,肝癌的死亡率呈现上升趋势.肝癌标化死亡率AAPC=-0.95,P>0.05;标化率1985-1998年呈上升趋势,APC=4.00,1998-2023年呈下降趋势,APC=-3.43,P<0.05.人口因素一直是肝癌死亡率升高的因素,人口因素的作用越来越明显,非人口因素作用在1995-1999年达到最大化,其后开始减弱,是2010-2023年死亡率下降的主要因素.结论 招远市肝癌死亡率虽然已呈下降趋势,但仍处于较高水平,是严重危害招远市居民健康的重要癌症.建议在招远市开展肝癌的早诊早治,降低肝癌死亡率.
Epidemiological characteristics and trend of liver cancer mortality in Zhaoyuan city,Shandong from 1985 to 2023
Objective To analyze the changes of liver cancer mortality rate in Zhaoyuan from 1985 to 2023,and provide a basis for the prevention and control of liver cancer.Methods Based on the monitoring data of all causes of death in Zhaoyuan City,liver cancer mortality data from 1985 to 2023 were extracted.Excel 2010 and SAS9.3 were used to calcu-late the crude mortality rates,standardized rates,cumulative rates and truncated rates;Joinpoint5.0 software was used to perform regression analysis on the age-standardized liver cancer mortality rates from 1985 to 2023,and the annual change percentage(APC)was calculated.The contribution of population factors and non-population factors was calculated by de-composing the differences in mortality rates.Results Totally 9 080 deaths of liver cancer were reported in Zhaoyuan city from 2008 to 2023.The crude mortality rate was 42.31/105,ranking third among malignant tumors following gastric cancer and lung cancer.The age-standardized mortality rate was 21.30/105 and the world-standardized rate was 28.03/105;The mortality rate of liver cancer showed an upward trend with increasing age.,The age-standardized mortality rate AAPC was-0.95,P>0.05.The standardized rate increased from 1985 to 1998,with an APC of 4.00,and decreaseed from 1998 to 2023,with an APC of-3.43,P<0.05.Population factors have always been a factor contributing to the increase in liver cancer mortality,and their role has become increasingly evident..non-demographic factors reached its maximum effect from 1995 to 1999,and then began to weaken,resulting the decrease in mortality rate from 2010 to 2023.Conclusions Although the mortality rate of liver cancer in Zhaoyuan City has shown a downward trend,it remains at a relatively high level and is a significant cancer that seriously endangers the health of Zhaoyuan residents.Early diag-nosis and early treatment is suggested to reduce the mortality of liver cancer in Zhaoyuan City.

liver cancermortalitytrendZhaoyuan city

翟玉庭、郝建辉、宁巍巍、王璐、赵梓旭、李桂刚、杨春晖

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招远市疾病预防控制中心慢性非传染性疾病防治科,山东招远 265400

招远市玲珑中心卫生院公共卫生科,山东招远 265400

招远市人民医院普外科,山东 招远 265400

肝癌 死亡率 变化趋势 招远市

2024

社区医学杂志
中华预防医学会

社区医学杂志

影响因子:0.588
ISSN:1672-4208
年,卷(期):2024.22(16)