首页|人呼吸道合胞病毒感染的预防和治疗研究进展

人呼吸道合胞病毒感染的预防和治疗研究进展

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呼吸道合胞病毒(respiratory syncytial virus,RSV)会引起呼吸道和肺部感染,尤其是婴幼儿和老人,容易出现严重感染.尽管RSV感染对医疗保健产生了全球性影响,目前仍以支持性的治疗为主.在过去的几十年中,随着对 RSV发病机制和免疫病理学的了解不断加深,RSV的预防策略取得了重大进步.自1966年 RSV 疫苗首次试验以来已经过去50多年,目前有两种RSV疫苗获批上市.综述了当前RSV感染的治疗方案(包括RSV 特异性和非特异性)以及RSV疫苗的研发进展,以期为RSV的治疗及疫苗的研发提供参考.
Advances on Prevention and Treatment of Human Respiratory Syncytial Virus
Respiratory syncytial virus(RSV)is a leading cause of respiratory and lung infections,especially in young children and the elderly,which are prone to serious infections.Despite the global impact of RSV infection on healthcare,the current ther-apy is still mostly supportive.Over the past few decades,our understanding of the pathogenesis and immunopathology of RSV had evolved,leading to significant advances in RSV prevention strategies.More than 50 years have passed since the RSV vac-cine was first trialed in 1966,and two RSV vaccines have been approved.In this paper,current treatment options for RSV infec-tion(including RSV-specific and non-specific)and the development progress of different RSV prevention vaccines were re-viewed,which was expected to provide reference for the treatment and vaccines research and development of RSV.

respiratory syncytial virus(RSV)monoclonal antibodiesantiviralvaccine

吕娜、李岩异、马祝青

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华北制药金坦生物技术股份有限公司,石家庄 050035

山东博安生物技术股份有限公司,山东 烟台 264003

呼吸道合胞病毒(RSV) 单克隆抗体 抗病毒 疫苗

2024

生物技术进展
中国农业科学院茶叶研究所 中国农业科学院生物科技研究所

生物技术进展

CSTPCD
影响因子:0.554
ISSN:2095-2341
年,卷(期):2024.14(1)
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