Hydrogen has attracted a lot of attention in energy field,at the same time,it is also a clean,efficient and economical technology in medical field.The field of hydrogen medicine mainly includes basic and clinical research on the effects of hydro-gen on diseases,such as the usage methods,dosage,health promoting effects,therapeutic effects on diseases,and mechanisms of action of hydrogen.Hydrogen can remove hydroxyl radicals and peroxynitrites,which have significant therapeutic effect for oxi-dative stress and inflammation related diseases.At the same time,as an endogenous gas,it is non-toxic and harmless,and will not cause adverse reactions to human body.Targeted treatment of brain and nervous system diseases,cardiovascular diseases,di-abetes,cancer and other diseases can be achieved through direct intake and controlled release.The article introduced the differ-ent ways of releasing hydrogen gas and its applications in the medical field,and looked forward to the scientific and practical is-sues of hydrogen medicine,in order to provide reference for the application research of hydrogen in the biomedical field.