Research Progress of Phosphite Dehydrogenase in Genetically Engineered Microorganisms and Plants
In recent years,agricultural production is facing the dual challenges of phosphorus deficiency and environmental pol-lution.The discovery and application of phosphite dehydrogenase(PTDH)provides a new idea to solve this problem.In microor-ganisms,PTDH makes efficient fermentation in non-sterile environments possible,reducing costs and increasing production effi-ciency.In plants,PTDH not only solves the problem of phosphorus source,but also provides a new way for the development of herbicides.In addition,the use of phosphite as a potential herbicide and phosphorus source is more environmentally friendly,low cost and stable than traditional herbicides.Although significant progress has been made in the application of phosphite dehy-drogenase,the current research is still in the stage of functional analysis and conceptual verification.The research on the catalyt-ic mechanism,protein structure and enzyme activity improvement of phosphite dehydrogenase needs to be further studied.This study reviewed the application of PTDH in microorganisms,model plants(such as Arabidopsis and tobacco),cash crops(such as cotton and rapeseed)and food crops(such as rice and corn).In the future,with the development of protein directed evolution technology,gene transformation and gene editing technology,the application effect of phosphite dehydrogenase will be further optimized,which will provide more possibilities for efficient utilization of phosphite and environmental protection of crops.
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维普
