In recent years,how to inhibit the proliferation of tumor cells and the expression of stem genes has become one of the focus-es of scientists in cancer treatment.Cancer stem cell(CSC)is a kind of cell group with self-renewal ability in tumors,and is consid-ered as one of the driving factors in the process of tumorigenesis.The Hippo signaling pathway is a highly conserved signaling pathway in biological evolution that plays an important role in cell proliferation,tissue development,and organ size.In this article,Hippo sig-naling pathway and its mechanism in cancer stem cell were briefly reviewed,and the prospect of tumor treatment was proposed,in order to provide reference for the development and future treatment of tumor stem cells.
维普
万方数据