Research Progress of Mitochondrial Biosynthesis in Diabetes Cardiomyopathy
Diabetic cardiomyopathy(DCM)is one of the most serious and common complications of diabetesmellitus(DM),and its pathogenesis is not well understood.A growing body of studies has shown that mitochondrial homeostasis is closely related to the development of DCM.Mitochondrial biosynthesis,as an important part of mitochondrial homeostasis,is involved in the oc-currence and development of DCM.Improving mitochondrial function by regulating molecular mechanisms related to mitochondri-al biosynthesis may be a new target for the prevention and treatment of DCM.Based on the literature at home and abrod in recent years,the mechanism and research progress of mitochondrial biosynthesis in DCM were summarized in order to provide a refer-ence for the prevention and treatment of DCM.