首页|微生物胞外多糖的来源、生物合成及功能研究进展

微生物胞外多糖的来源、生物合成及功能研究进展

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胞外多糖是由微生物合成的一种功能多样的聚糖化合物.近年来研究发现,胞外多糖具有吸附性、亲水性、粘结性及免疫活性等特性,在多学科研究中受到广泛关注.目前胞外多糖的生产和提纯过程存在成本高、收率低等问题,阻碍了其规模化生产和商业应用.系统介绍了胞外多糖的微生物来源、生物学特征和生理功能,重点阐述了几种具有工业应用潜力的胞外多糖的生物合成机制,列举了胞外多糖最新的应用方向,并对胞外多糖的生物合成机制以及胞外多糖的规模化生产和多领域应用进行了展望.希望为进一步开发利用胞外多糖产生菌的菌种资源、深入研究微生物胞外多糖功能和活性机制以及发酵生产过程、以及对胞外多糖在多学科和多领域的广泛应用的优化提供参考.
Research Progress in Source,Biosynthesis and Function of Microbial Exopolysaccharides
Exopolysaccharides are multifunctional glycan compounds synthesized by microorganisms.In recent years,it has been found that exopolysaccharides have the functions of adsorption,hydrophilicity,cohesiveness and immune activity,which have attracted extensive attention in the field of multidisciplinary researches.At present,the production and purification process of exopoly-saccharides has several problems,such as high cost and low yield,which limit the large-scale production and commercial applica-tion.In this review,the microbial sources,biological characteristics and physiological functions of exopolysaccharides were system-atically introduced,the biosynthetic mechanisms of several exopolysaccharides with industrial application potentials were emphati-cally summarized,and the latest application directions of exopolysaccharides were listed.Moreover,the biosynthetic mechanisms,the large-scale production,and multi-field application of exopolysaccharides were prospected.Therefore,this review was expected to pro-vide a reference for the further development and utilization,in-depth study of the function and activity mechanism,and the optimization of fermentation production process of microbial exopolysaccharides,and the extensive application in multiple disciplines and fields.

exopolysaccharidesmicroorganismstructural characteristicsynthetic pathway

徐畅、刘天一、刘文佳、张俐敏、莫继先

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齐齐哈尔大学生命科学与农林学院,黑龙江 齐齐哈尔 161006

胞外多糖 微生物 结构特性 合成途径

黑龙江省省属高校基本科研业务费专项黑龙江省大学生创新创业训练计划

135409420S202310232017

2024

生物技术进展
中国农业科学院茶叶研究所 中国农业科学院生物科技研究所

生物技术进展

CSTPCD
影响因子:0.554
ISSN:2095-2341
年,卷(期):2024.14(3)
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