Progress in the Application of Deuterium and its Labeled Compounds in Biomedical Research
Stable isotopes are widely used in fields such as medicine,food safety,and ecological environment due to their charac-teristics of no radioactivity and good stability.Deuterium is a stable isotope of hydrogen element,and deuterium labeling method has the advantages of simplicity,speed,and low cost.Researches have shown that deuterium isotope labeling has enormous potential for application in the field of life sciences such as metabolic mechanisms,disease prevention and treatment targets,pharmacology,etc.The review summarized the synthesis methods,detection techniques,and applications of deuterium and its compounds in biomedical research,and prospected for the future development,in order to provide reference for researchers and applications in related fields.