Research Progress on Structure and Function of Lentinan
Lentinula edodes,as an important edible fungus in China,has a long history of cultivation.It is now widely used in the fields of food and medicine worldwide.Lentinula edodes is rich in bioactive polysaccharides,especially β-glucan.Since the dis-covery of the anticancer biological activity of lentinan in the 1970 s,the research on the activity of lentinan has never stopped.Studies have shown that lentinan possesses a variety of significant biological activities,including antioxidant,anti-tumor,anti-aging,anti-inflammatory,immunomodulatory,antiviral,hepatoprotective,and cholesterol-lowering effects.The isolation,puri-fication,chemical properties,and biological activities of lentinan have always attracted close attention from scholars around the world.Based on the previous work,this article comprehensively summarized the latest research progress of lentinan,including the separation methods of lentinan and the impact of different separation methods on its structural activity,the relationship be-tween structural characteristics and polysaccharide biological activity,and the mechanism of action of lentinan in exerting biolog-ical activity.The paper was expected to provide valuable information references for the further application of lentinan in the fields of medical treatment and functional foods.
NETL
NSTL
万方数据
