摘要
维吾尔族药材(简称维药)苦白蹄是一种常用的民族药材,主要源自多孔菌科拟层孔菌属中的苦白蹄Fomes officinalis(Vill.ex Fr.)Ames的子实体.详尽考证了维药苦白蹄的名称、基原、药性、功效及其复方制剂,系统整理了从苦白蹄中分离并鉴定出的三萜酸类、甾醇类、芳香类、倍半萜类及其他化学成分,并对维药苦白蹄进行了现代药理学分析.现有研究表明,维药苦白蹄具有抗肿瘤、抗氧化、调节免疫、止咳祛痰、抗阿尔兹海默病及抗菌、抗炎、抗衰老等多种药理作用.鉴于苦白蹄丰富的药用价值及其巨大的开发潜力,总结了其本草考证、化学成分及现代药理研究的进展,旨在为维药苦白蹄的临床应用与开发提供参考.
Abstract
The Uyghur medicine Fomes officinalis(Vill.ex Fr.)Ames is a commonly used ethnic medicine,mainly the fruiting body of Ames in the polyporus fungi family.In this paper,the name,origin,drug properties,efficacy and compound preparations of Fomes officinalis(Vill.ex Fr.)Ames,a Uygur medicine,were collated.The triterpenoid acid,sterols,aromatics,sesquiterpene and other chemical components isolated and identified from Fomes officinalis(Vill.ex Fr.)Ames were systematically sorted out and the modern pharmacological analysis was conducted on Uyghur Fomes officinalis(Vill.ex Fr.)Ames.At present,it is known that the Uyghur medicine Fomes officinalis(Vill.ex Fr.)Ames has multiple pharmacological effects such as anti-tumor,antioxi-dant,immune regulation,cough and expectorant,anti Alzheimer's disease,antibacterial,anti-inflammatory,anti-aging,etc.Given the rich medicinal value and enormous development potential of Fomes officinalis(Vill.ex Fr.),this article reviewed the progress its herbal research,chemical composition,and modern pharmacological research,aiming to provide reference for the clinical application and development of Uyghur medicine.
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