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暴马桑黄的抗肿瘤活性成分及其作用机制研究进展

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暴马桑黄(Sanghuangporus baumii)作为一类大型药用真菌,不仅是中国传统中备受推崇的名贵中药材,更随着近年来菌类栽培学研究的迅猛发展,已经成为人工种植桑黄的主要菌种.现代研究发现,暴马桑黄中含有的黄酮类、多糖类、多酚类和萜类等多种化学成分,具有抗肿瘤、抗氧化、抗炎、保肝和抗肝硬化等药理活性.系统整理了暴马桑黄中抗肿瘤活性成分的提取与分离方法,总结了暴马桑黄抑制肿瘤细胞的作用机制,以期为暴马桑黄在医药领域的研究与应用提供理论参考.
Research Progress on Antitumor Active Constituents and Their Mechanism of Action of Traditional Chinese Medicine Sanghuangporus baumii
Sanghuangporus baumii is a kind of large medicinal fungus,not only a precious traditional Chinese medicinal herb,but also has become the main strain for artificial cultivation of Sanghuang.The modern research has been found that Sanghuang contains various chemical components such as flavonoids,polysaccharides,polyphenols,and terpenes,and has pharmacologi-cal activities such as anti-tumor,antioxidant,anti-inflammatory,hepatoprotective,and anti-liver cirrhosis.The article systemati-cally organized the extraction and separation methods of the anti-tumor active components in Sanghuang,and elaborated on the ways to achieve the inhibitory effect of Sanghuang on tumor cell,in order to provide theoretical reference for the research and ap-plication of Sanghuang in the field of medicine.

Sanghuangporus baumiiactive ingredientextraction and isolationanti-tumor

孙恺婧、刘馨泽、金鑫、杨雪、王琦、李玉、陈长宝、万茜淋

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长春中医药大学吉林省人参科学研究院,长春 130117

东北师范大学,分子表观遗传学教育部重点实验室,长春 130024

长春中医药大学附属医院心血管医学与心脏康复中心,长春 130021

吉林农业大学食药用菌教育部工程研究中心,长春 130118

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暴马桑黄 活性成分 提取分离 抗肿瘤

2024

生物技术进展
中国农业科学院茶叶研究所 中国农业科学院生物科技研究所

生物技术进展

CSTPCD
影响因子:0.554
ISSN:2095-2341
年,卷(期):2024.14(6)