Cellular senescence is a biological process characterized by the dysfunction of cells,along with a decline in cell differentiation and proliferation.Senescent cells exhibit some notable changes,including epigenetic remodeling of chromatin,alterations in the abundance and function of organelles,and an increase in the secretion of pro-inflammatory factors.This paper outlines the eight widely recognized hallmark changes associated with cellular senescence and their typical mechanisms of action,to provide cutting-edge teaching materials on cellular senescence for senior high school biology teaching.
关键词
衰老/细胞衰老/变化特征/信号通路
Key words
senescence/cellular senescence/traits of change/signaling pathway
维普
万方数据