Extraction and antibacterial activity screening of soil microbes from saline-alkali soil of northern Ningxia
45 single colonies with certain morphological characteristics were isolated from saline-alkali soil in northern Ningxia,and the 16S rRNA sequence of the strains were sequenced and identified by genome extraction technology.Results showed that there were 16 strains of actinomycetes,including 13 strains of Streptomyces,3 strains of Acidophilum.The experimental results of antibacterial ac-tivity exhibited that all 16 strains of actinomycetes had antibacterial activity,among which 12 strains of secondary metabolites had sig-nificant antibacterial activity against Proteus vulgaris,12 strains of secondary metabolites had obvious inhibitory activity against Staphy-lococcus aureus,and 9 strains of secondary metabolites had certain growth inhibitory activity against Candida albicans.The researches demonstrated that the microbial strains isolated from saline-alkali soil in northern Ningxia had strong antibacterial or bacteriostatic ac-tivity.This study not only enriched the microbial resources in special habitats,but also laid a foundation for further isolation of antibac-terial lead compounds.