Effects of grape seed procyanidins on immune function and antioxidant capacity in weaned piglets
Obj ective]The trial was conducted to investigate effects of grape seed procyanidins (GSP)on immune func-tion and antioxidant capacity in weaned piglets.[Methods]A total of 128 Duroc×Landrace×Yorkshine piglets weaned at 2 1 days of age were randomly assigned to one of the four treatment groups with 4 replicate pens per group and 8 pig-lets per pen.The treatments included control group (fed a basal corn-soybean meal diet,BD)and three different GSP level groups (BD+50,100,150 mg·kg-1 GSP respectively).The trial lasted 28 days.Blood samples were collected on d 14 and 28 for the measurement of serum immune parameters and antioxidant indices.[Results]Pigs offered diets sup-plemented with GSP at doses of 100 or 150 mg·kg-1 generated higher (P<0.05)serum immunoglobulin (Ig)G,IgM, complement 4 (C4)and interleukin-2 (IL-2)concentrations,produced stronger (P<0.05)serum T-AOC,GSH-Px and SOD activities and lower serum MDA content than those fed basal diet.[Conclusion]Administration of GSP in weaned piglets diet had beneficial effects on immune responses and antioxidant abilities suggested in weaned piglets.
国家科技期刊平台
NSTL
万方数据
维普
