Study on triterpenoids from the fruits of Melia toosendan Sieb.Et Zucc.
Objective To study triterpenoids from the fruits of Melia toosendan Sieb.Et Zucc..Methods The ethyl acetate extracts of M.toosendan were isolated and purified by silica gel column chromatography and ostade-cylsilane reversed phase column chromato-graphy.The compounds were identified by physicochemical methods and spectral data analyses.Results Five triterpenoids were obtained from the fruits of M.toosendan and identified as(21S,23R,24R)-21,23-epoxy-21,24-dihydroxy-25-methoxytirucall-7-en-3-one(compound 1),Cinamodiol,Meliasenin G,21R,23R-epoxy-21α-ethoxy-24S,25-dihydroxy-apotirucall-7-en-3-one,Toosendine E,respectively.Conclusion All compounds are tirucallane-type triterpenoid derivatives.It is the first time that compound 1 is isolated from the fruits of M.toosendan.
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