Biological characteristics and in vitro antibacterial activity of Kerstersia gyiorum in respiratory tract specimens
Objective To explore the basic biological characteristics and the drug sensitivity of Kerstersia gyiorum,and provide guidance and help for the identification and the clinical rational use of the bacterium.Method According to age,gender,and main diagnosis,10 respiratory specimens from clinical sources were statistically analyzed.Strain identification was performed by bacterial culture,Gram staining,and matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MALDI-TOF MS),and its biological characteristics were analyzed by basic biochemical reaction experiments.In vitro drug susceptibility analysis was performed by the VITEK 2 fully automated microbial identification and antimicrobial susceptibility system.Result Kerstersia gyiorum was more common in middle-aged and elderly men with underlying diseases and long-term inflammation.Clinically,it was easy to co-infect with other bacteria.The general bacterial culture results showed that the bacteria were grayish-white on blood plates and chocolate plates containing vancomycin,and light purple on MacConkey plates,and the colonies showed rough surface and migratory growth.Microscopically it was Gram-negative cocci and identified by MALDI-TOF MS as Kerstersia gyiorum.After comprehensive analysis of the drug susceptibility results of the bacterium,it was intermediate or resistant to quinolone antibiotics,and sensitive to penicillins,cephalosporins,enzyme inhibitors,and carbapenems.Conclusion Kerstersia gyiorum is a Gram-negative coccus bacterium and often co-infected with other bacteria.Quinolone antibiotics are not firstly recommended in clinical for this bacterium.
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