首页|基于因子分析探讨急性胰腺炎早期诊断的敏感性指标及中医证型分布规律研究

基于因子分析探讨急性胰腺炎早期诊断的敏感性指标及中医证型分布规律研究

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目的 通过因子分析探索急性胰腺炎早期诊断的血清生化指标及中医证型分布规律研究。方法 选取陕西中医药大学附属医院消化科 2021 年 1 月—2021 年 5 月确诊为急性胰腺炎的 65 例患者为研究组,65 例体检正常者为对照组,建立首诊血清生化指标,对其进行因子分析法评价各指标的主成分,并进一步确定急性胰腺炎早期诊断的敏感指标。对研究组 65 例进行中医证型分布规律研究。结果 急性胰腺炎血清生化指标经因子分析后,提取到 5 个成分,敏感性指标排序依次为中性粒细胞百分比、乳酸脱氢酶、白细胞、淀粉酶、脂肪酶、谷草转氨酶。急性胰腺炎中医证型按照从高到低依次为:肝郁气滞型,肝胆湿热型,腑实热结型,瘀毒互结型,内闭外脱型。结论 利用因子分析可以揭示急性胰腺炎血清生化指标的潜在联系,为进一步探索急性胰腺炎早期诊断的敏感指标提供了依据;中性粒细胞百分比、乳酸脱氢酶、白细胞、淀粉酶、脂肪酶、谷草转氨酶可作为急性胰腺炎早期诊断的重要血清生化指标。急性胰腺炎中医证型分布以肝郁气滞型最为常见,是急性胰腺炎早期的常见证型。
Study on Sensitivity Indicators and Distribution Patterns of Traditional Chinese Medicine Syndrome Types for Early Diagnosis of Acute Pancreatitis Based on Factor Analysis
Objective To explore the distribution patterns of serum biochemical indicators and traditional Chinese medicine syndrome types for early diagnosis of acute pancreatitis through factor analysis.Methods 65 patients diagnosed with acute pancreatitis in the Digestive Department of Affiliated Hospital of Shaanxi University of Chinese Medicine from January 2021 to May 2021 were selected as the study group,and 65 healthy individuals were selected as the control group.First visit serum biochemical indicators were established,and factor analysis was used to evaluate the principal components of each indicator and further determine the sensitive indicators for early diagnosis of acute pancreatitis.Conduct a study on the distribution pattern of traditional Chinese medicine syndrome types in 65 cases of the research group.Results After factor analysis,five components were extracted from the serum biochemical indicators of acute pancreatitis.The sensitivity indicators were ranked as neutrophil percentage,lactate dehydrogenase,white blood cells,amylase,lipase,and aspartate aminotransferase.The traditional Chinese medicine syndrome types of acute pancreatitis,from high to low,are:liver stagnation and Qi stagnation type,liver and gallbladder damp heat type,excessive heat accumulation type,blood stasis toxin mutual accumulation type,and internal closure and external detachment type.Conclusion Factor analysis can reveal the potential correlation between serum biochemical indicators in acute pancreatitis,providing a basis for further exploration of sensitive indicators for early diagnosis of acute pancreatitis;Neutrophil percentage,lactate dehydrogenase,white blood cells,amylase,lipase,and aspartate aminotransferase can be important serum biochemical indicators for early diagnosis of acute pancreatitis.The distribution of TCM syndrome types in acute pancreatitis is most common in the liver stagnation and Qi stagnation type,which is a common syndrome type in the early stage of acute pancreatitis.

Factor analysisAcute pancreatitisEarly diagnosisSensitive indicatorsTraditional Chinese medicine syn-drome typesDistribution pattern

胡卫敏、马小兵、王喜霞、袁敏惠、苏彦娥、周嘉迪、马驰

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陕西中医药大学附属医院,陕西 咸阳 712000

陕西中医药大学第二附属医院,陕西 西安 712046

因子分析 急性胰腺炎 早期诊断 敏感指标 中医证型 分布规律

2025

陕西中医药大学学报
陕西中医学院

陕西中医药大学学报

影响因子:0.479
ISSN:2096-1340
年,卷(期):2025.48(1)