Research Progress on the Application of Zebrafish Model in the Prevention and Treatment of Osteoporosis with Traditional Chinese Medicine
With the continuous development of osteoporosis(OP)animal models,zebrafish has gradually become one of the commonly used animal models in traditional Chinese medicine for the prevention and treatment of OP.This paper summarized the application of zebrafish as animal model in OP prevention and treatment in the past five years,and systematically reviewed the establishment of different zebrafish OP models,and the research progress in the pharmacology and toxicology of zebrafish on monomer Chinese medicine,Chinese herbal compound and traditional Chinese patent medicines and simple preparations on OP prevention and treatment.In order to provide new ideas and methods for the pathogenesis of OP and the selection of animal models for screening and studying anti OP drugs.
OsteoporosisTraditional Chinese MedicineZebrafishAnimal modelsBone metabolism