首页|老年晚期肺癌患者急性非大面积肺栓塞的影响因素分析

老年晚期肺癌患者急性非大面积肺栓塞的影响因素分析

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目的 探究老年晚期肺癌(ALC)患者产生急性非大面积肺栓塞(PE)的影响因素.方法 选取145例老年ALC患者为研究对象,将住院时产生急性非大面积PE的48例患者划分成观察组,未产生急性非大面积PE的97例患者划分为对照组.统计2组性别、年龄、吸烟史等临床有关资料,采用Logistic回归分析探究老年ALC患者产生急性非大面积PE的危险因素.结果 单因素分析显示:性别、年龄、体重指数(BMI)、手术史、PE史、高血压病史、血小板计数、病理类型与老年ALC患者产生急性非大面积PE无关(P>0.05);D-二聚体(D-D)、红细胞比容、TNM分期、纤维蛋白原(FIB)、吸烟史、血红蛋白与患者产生急性非大面积PE有关(P<0.05).多因素Logistic回归分析显示:D-D≥500μg/L、红细胞比容<0.35%、TNM Ⅲ~Ⅳ期、FIB高、有吸烟史、血红蛋白>140 g/L为老年肺癌患者产生急性非大面积PE的主要影响因素(P<0.05).结论 老年ALC患者产生急性非大面积PE影响因素众多,与D-D≥500 μg/L、红细胞比容<0.35%、TNM Ⅲ~Ⅳ期、FIB高、有吸烟史、血红蛋白>140 g/L等相关,临床需予以积极重视.
Analysis of Influencing Factors of Acute Non Massive Pulmonary Embolism in Elderly Patients with Advanced Lung Cancer
Objective To explore the influencing factors of acute non massive pulmonary embolism(PE)in elderly pa-tients with advanced lung cancer(ALC).Methods 145 elderly patients with ALC were selected as the study subjects.48 pa-tients with acute non large area PE during hospitalization were divided into the observation group,and 97 patients without acute non large area PE were divided into the control group.Statistical analysis was conducted to investigate the risk factors of acute non large area PE in elderly patients with ALC by using clinical data such as gender,age,smoking history,and logistic regression anal-ysis.Results Single factor analysis showed that gender,age,body mass index(BMI),surgical history,PE history,hypertension history,platelet count,and pathological type were not significantly associated with acute non large area PE in elderly patients with ALC(P>0.05);D-dimer(D-D),hematocrit,TNM stage,fibrinogen(FIB),smoking history,and hemoglobin were significantly associated with acute non large area PE in patients(P<0.05).Multivariate logistic regression analysis showed that D-D ≥500μg/L,hematocrit<0.35%,TNM stage Ⅲ~Ⅳ,high FIB,smoking history,and hemoglobin>140 g/L were the main influencing factors for acute non large area PE in elderly lung cancer patients(P<0.05).Conclusion There are many factors influencing the occurrence of acute non large area PE in elderly patients with ALC,which are related to D-D≥500 μg/L,hematocrit<0.35%,TNM stage Ⅲ~Ⅳ,high FIB,smoking history,hemoglobin>140 g/L,and other related factors need to be actively paid attention to in clinical practice.

Senile advanced lung cancerAcute non massive pulmonary embolismInfluence factor

王素娥、姚德胜、赵国伟

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453000 解放军陆军第八十三集团军医院

老年晚期肺癌 急性非大面积肺栓塞 影响因素

2024

实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
年,卷(期):2024.39(1)
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