Clinical and Pathological Characteristics and Prognosis Analysis of Patients with Acute Coronary Syndrome Combined with Malignant Tumors
Objective To study the clinical and pathological characteristics of patients with acute coronary syndrome(ACS)complicated with malignant tumors and the long-term prognosis after percutaneous coronary intervention(PCI).Methods 86 ACS patients with malignant tumors were selected as the combination group,and 86 ACS patients without malignant tumors who underwent PCI treatment at the same time were selected as the control group in a 1:1 ratio.Collect and analyze general baseline data,past medical history,clinical and ultrasound examinations,drug treatment status,PCI related data,and long-term prognosis of the 2 groups of patients.Results There were no significant changes in gender,age,BMI index,past medical history between the combined group and the control group(P＞0.05);The combined group had higher levels of high blood pressure(SBP),low blood pressure(DBP),heart rate(HR),ventricular ejection fraction(LVEF),and glomerular filtration rate(eGFR)compared to the control group(P＜0.05);Combination group aspirin β There were no significant changes in the use of receptor blockers,P2Y12 receptor inhibitors,angiotensin converting enzyme(ACEI),diuretics,and statins compared to the control group(P＞0.05);The CTO lesions in the combined group were higher than those in the control group,and the calcification lesions were low-er than those in the control group(P＜0.05);There were no significant changes in the type of ACS,number of diseased vessels,left main artery disease,bifurcation disease,and number of stent implantation in the combined group compared to the control group(P＞0.05).The incidence of vascular remodeling in the combined group was lower than that in the control group(P＜0.05);The incidence of cardiovascular and cerebrovascular adverse events(MACCE),cardiovascular death,non fatal cardiovascular death,non fatal myocardial infarction,stroke,myocardial infarction thrombolysis(T1MI)massive bleeding,all cause death,tumor death,cardiogenic shock,readmission,re PCI,and re coronary artery bypass grafting(CABG)in the combined group showed no significant changes compared to the control group(P＞0.05).Conclusion Malignant tumors have a significant incidence rate after PCI.Compared with patients with ACS alone,patients with ACS combined with malignant tumors have a higher incidence of long-term cardiovascular adverse events and a poor long-term prognosis.
Acute coronary syndromeMalignant tumorPercutaneous coronary interventionLong term prognosis
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