Analysis of Related Risk Factors of Postoperative Pulmonary Infection in Patients Under-went Radical Esophageal Cancer
Objective To investigate the relevant risk factors of pulmonary infection after radical surgery in patients with esophageal cancer.Methods The clinical data of 120 patients with oesophageal cancer were also retrospectively analyzed.All pa-tients were treated with radical esophageal cancer,and were divided into infection and non-infection groups according to whether lung infection occurred after surgery.Baseline data of age,sex,body quality index and other data of the 2 groups were collected.Independent risk factors affecting the occurrence of postoperative lung infection in esophageal cancer patients were obtained by lo-gistic regression analysis.Results A total of 26 postoperative pulmonary infections occurred in 120 patients,The incidence rate was 21.67%(26/120);The univariate analysis revealed that,age,operative time,intraoperative bleeding volume,preoperative al-bumin level,mode of surgical ventilation,diabetes mellitus,COPD,smoking history,and preoperative pulmonary function were as-sociated with the occurrence of postoperative pulmonary infection,The difference was statistically significant(P<0.05);Multiva-riate analysis revealed that age≥65 years,operative time≥4 h,intraoperative bleeding volume≥200 mL,preoperative albumin level<30 g/L,single lung ventilation,diabetes,COPD,smoking history,and preoperative pulmonary function(FEV1/FVC)<70%were independent risk factors affecting the occurrence of postoperative pulmonary infection(P<0.05 and OR>1).Conclu-sion The risk of lung infection in esophageal cancer patients after radical surgery is high,which is closely related to age,opera-tion time,intraoperative bleeding volume,and preoperative albumin level.Targeted clinical intervention should be carried out as early as possible to reduce the occurrence of lung infection.
Pulmonary infectionRadical resection of esophageal cancerInfluencing factors