Correlation Between Visceral Pleural Involvement and Lymph Node Metastasis in Clinical Tis～T1 Non-small Cell Lung Cancer
Objective To investigate the correlation between visceral pleural involvement and lymph node metastasis in clinical Tis～T1 non-small cell lung cancer(NSCLC).Methods The clinical data of 84 patients with Tis～T1 stage NSCLC were retrospectively analyzed.All patients were treated with lobectomy + systematic lymph node dissection.After the operation,pathological specimens were sent for examination to determine the status of pleural visceral infiltration(VPI).According to VPI,the patients were divided into PL0 group and PL1/PL2 group.The data of age,sex,body mass index,basic disease,tumor size,pathological type,tumor location,vascular tumor thrombus,preoperative carcinoembryonic antigen(CEA),basic disease and lymph node metastasis were collected.The relationship between VPI and clinicopathological features and the relationship between VPI and lymph node metastasis were analyzed.Results Among the 84 patients,18 were complicated with VPI,and the incidence of visceral pleural involvement was 21.43%(18/84);The proportion of tumor size 2～3 cm and preoperative CEA level≥3.5 ng/l in PL1/PL2 group was higher than that in PL0 group(P<0.05);The lymph node metastasis rate and N2 rate in PL1/PL2 group were higher than those in PL0 group(P<0.05).Conclusion There is a close relationship between VPI and lymph node metas-tasis in patients with Tis～T1 stage NSCLC.When combined with VPI,lymph node metastasis should be considered.Extensive lymph node dissection should be performed during operation to avoid recurrence and metastasis after operation.
万方数据
维普
