实用癌症杂志2024,Vol.39Issue(2) :263-266.DOI:10.3969/j.issn.1001-5930.2024.02.024

老年肺癌患者术前气道定植菌及术后肺部并发症发生的相关因素研究

A Study on the Related Factors of Preoperative Airway Colonization Bacteria and Postoperative Pulmonary Complications in Elderly Lung Cancer Patients

牛丹丹 董永军 李海明
实用癌症杂志2024,Vol.39Issue(2) :263-266.DOI:10.3969/j.issn.1001-5930.2024.02.024

老年肺癌患者术前气道定植菌及术后肺部并发症发生的相关因素研究

A Study on the Related Factors of Preoperative Airway Colonization Bacteria and Postoperative Pulmonary Complications in Elderly Lung Cancer Patients

牛丹丹 1董永军 1李海明1
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作者信息

  • 1. 463000 河南省驻马店市中心医院
  • 折叠

摘要

目的 探讨老年肺癌患者术前定植菌及术后肺部并发症发生的危险因素.方法 回顾性分析 80 例老年肺癌患者的临床资料.所有患者术前均行气道定植菌筛查,依据是否存在气道定植菌分阳性组与阴性组,分析老年肺癌患者术前气道定植菌的危险因素;术后依据是否发生肺部并发症分为发生组与未发生组,分析影响老年肺癌患者术后肺部并发症的危险因素.结果 80 例老年肺癌患者中气道定植菌阳性率为 37.50%(30/80),术后肺部并发症发生率为36.25%(29/80);单因素分析显示,SP-D、吸烟史与老年肺癌患者术前气道定植菌有关(P<0.05);多因素显示,SP-D<30 ng/ml、吸烟为影响老年肺癌术前气道定植菌的高危因素(P<0.05 且OR>1);单因素显示,年龄、SP-D、吸烟史、气道定植菌、手术时间与老年肺癌术后肺部并发症的发生有关(P<0.05);多因素显示,年龄≥70 岁、SP-D<30 ng/ml、吸烟、气道定植菌阳性、手术时间≥2h为老年肺癌术后肺部并发症发生的高危因素(P<0.05 且OR>1).结论 老年肺癌患者受SP-D<30 ng/ml、吸烟等影响,术前气道定植菌阳性较高,而年龄≥70 岁、SP-D<30 ng/ml、吸烟、气道定植菌阳性、手术时间≥2h为老年肺癌术后肺部并发症发生的高危因素,临床据此在围术期采取针对性干预措施,以降低术后肺部并发症风险.

Abstract

Objective To explore the risk factors for preoperative colonization of bacteria and postoperative pulmonary complications in elderly lung cancer patients.Methods A retrospective analysis was conducted on the clinical data of 80 elderly lung cancer patients.All patients underwent preoperative screening for airway colonization bacteria,and the risk factors for preop-erative airway colonization bacteria in elderly lung cancer patients were analyzed based on the presence of positive and negative airway colonization bacteria;After surgery,patients were divided into 2 groups based on the occurrence of pulmonary complica-tions:the occurrence group and the non occurrence group.The risk factors affecting postoperative pulmonary complications in eld-erly lung cancer patients were analyzed.Results The positive rate of airway colonization bacteria in 80 elderly lung cancer pa-tients was 37.50%(30/80),and the incidence of postoperative pulmonary complications was 36.25%(29/80);Univariate analy-sis showed that SP-D and smoking history were associated with preoperative airway colonization bacteria in elderly lung cancer pa-tients(P<0.05);Multivariate analysis showed that SP-D<30ng/ml and smoking were high-risk factors affecting preoperative air-way colonization bacteria in elderly patients with lung cancer(P<0.05 and OR>1);Univariate analysis showed that age,SP-D,smoking history,airway colonization bacteria,and surgery time were associated with the occurrence of postoperative pulmonary complications in elderly patients with lung cancer(P<0.05);Multivariate analysis showed that age≥70 years,SP-D<30ng/ml,smoking,positive airway colonization bacteria,and surgery time≥2 hours were high-risk factors for postoperative pulmonary com-plications in elderly patients with lung cancer(P<0.05 and OR>1).Conclusion Elderly lung cancer patients are affected by factors such as SP-D<30ng/ml and smoking,and preoperative positive airway colonization bacteria are higher.However,age≥70 years,SP-D<30ng/ml,smoking,positive airway colonization bacteria,and surgery time≥2 hours are high-risk factors for postop-erative pulmonary complications in elderly lung cancer patients.Based on this,targeted interventions should be taken during the perioperative period to reduce the risk of postoperative pulmonary complications.

关键词

肺癌/手术/气道定植菌/肺部并发症/危险因素

Key words

Lung cancer/Operation/Airway colonization bacteria/Pulmonary complications/Risk factors

引用本文复制引用

出版年

2024
实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
参考文献量11
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