Effect of Sentinel Lymph Node Biopsy and Axillary Lymph Node Dissection on Breast Cancer
Objective To investigate the clinical effect of sentinel lymph node biopsy and axillary lymph node dissection in the treatment of breast cancer.Methods Clinical data of 86 female breast cancer patients were retrospectively analyzed.43 patients treated with sentinel lymph node biopsy were treated as the observation group,and 43 patients treated with axillary lymph node dissection were treated as the control group.The surgical conditions,shoulder mobility,shoulder function,pain level,immune function,and complications were compared between the 2 groups.Results The intraoperative bleeding volume in the observation group[(76.52±6.29)ml]was less than that in the control group[(89.74±7.35)ml],Operation time[(62.35±6.25)min],extubation time[(4.35±0.49)d],and hospitalization time[(8.63±1.12)d]was shorter than the control group[(69.74±6.48)min,(5.24±0.67)d,(10.39±1.35)d],Statistical difference(P<0.05);External rotation[(76.24±5.73)],internal rotation[(74.14±5.82)],flexion[(150.32±9.82)],abduction[(137.52±9.43)],and shoulder Neer score[(86.32±6.15)]were higher than the control group[(68.78±5.42),(67.06±5.49),(138.97±9.37),(122.37±9.26),(80.54±6.07)points],Statistical difference(P<0.05);The visual simulation score(VAS)score[(5.21±1.17(1.17),(3.15±0.46),0.29)]at 1 d,3 d,7 d and 7 d was lower than the control group[(6.87±1.22),(3.87±0.52),(2.04±0.32)],Statistical difference(P<0.05);The observed group had postoperative CD3+[(65.28±6.19)%],CD4+[(43.76±4.28)%],CD4+/CD8+[(1.90±0.29)]higher than the control group[(60.14±6.05)%,(40.15±4.19)%,(1.49±0.28)],The CD8+[(23.04±2.25)%]was lower than that in the control group[(26.81±2.34)%],The complica-tion rate was lower than that in the control group,Statistical difference(P<0.05).Conclusion Sentinel lymph node biopsy can reduce the impact of surgery on shoulder joint function,and have less impact on immune function and fewer complications.
Breast cancerSentinel lymph node biopsyAxillary lymph node dissectionShoulder function
万方数据
维普
