首页|核磁共振联合多模态超声检查鉴别诊断乳腺肿瘤良恶性的临床价值

核磁共振联合多模态超声检查鉴别诊断乳腺肿瘤良恶性的临床价值

Clinical Effectiveness of Magnetic Resonance Imaging Combined with Multimodal Ultra-sound in Differential Diagnosis of Benign and Malignant Breast Tumors

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目的 探讨核磁共振(MRI)联合多模态超声在乳腺肿瘤良恶性中的鉴别诊断效能.方法 选取92 例女性乳腺占位性病变患者为研究对象.对所有患者施行MRI与多模态超声检查,以病理检查结果为"金标准",探究MRI +多模态超声联合检查对诊断乳腺肿瘤良恶性的应用价值.结果 92 例乳腺占位性病变患者经病理检查证实为恶性有31 例(33.70%),良性有61 例(66.30%);MRI联合多模态超声共检查出30 例为恶性,MRI共检查出25 例为恶性,而多模态超声共检查出23 例为恶性;MRI联合多模态超声检查在鉴别诊断乳腺肿瘤良恶性的灵敏度[93.55%(29/31)]、准确度[96.74%(89/92)]、阴性预测值[96.77%(60/62)]高于MRI、多模态超声单独检查,差异有统计学意义(P<0.05);MRI、多模态超声单独及联合检查的特异度、阳性预测值相比,差异无统计学意义(P>0.05).kappa检验显示:MRI联合多模态超声检查结果与"金标准"的一致性极好(kappa值=0.926,P =0.000);MRI与多模态超声单独检查与"金标准"的一致性较为理想(kappa值=0.636、0.642,P =0.000、0.000).结论 MRI联合多模态超声鉴别诊断乳腺肿瘤良恶性的效果显著,可有效提高恶性肿瘤诊断灵敏度与准确度,临床应用价值较高,值得大力推行.
Objective To explore the differential diagnostic efficacy of magnetic resonance imaging(MRI)combined with multimodal ultrasound in breast tumors.Methods 92 female patients with breast occupying lesions were selected as the re-search subjects.MRI and multimodal ultrasound were performed on all patients,with pathological examination results as the"gold standard"to explore the application effect of MRI +multimodal ultrasound combined examination for benign and malignant breast tumors.Results Among the 92 cases of breast occupying lesions,31 cases(33.70%)were confirmed as malignant and 61 cases(66.30%)as benign by pathological examination;A total of 30 cases were diagnosed as malignant by MRI combined with multi-modal ultrasound,25 cases were diagnosed as malignant by MRI,and 23 cases were diagnosed as malignant by multimodal ultra-sound;The sensitivity[93.55%(29/31)],accuracy[96.74%(89/92)],and negative predictive value[96.77%(60/62)]of MRI combined with multimodal ultrasound in the differential diagnosis of breast tumors were higher than those of MRI and multi-modal ultrasound alone,with statistically significant differences(P<0.05);There was no statistically significant difference in the specificity and positive predictive value between MRI and multimodal ultrasound alone and in combination(P>0.05).The Kappa test showed excellent consistency between the results of MRI combined with multimodal ultrasound and the"gold standard"(Kap-pa value =0.926,P =0.000);The consistency between MRI and multimodal ultrasound alone and the"gold standard"was rela-tively ideal(kappa values =0.636,0.642,P =0.000,0.000).Conclusion The combination of MRI and multimodal ultrasound has a significant effect in the differential diagnosis of benign and malignant breast tumors,which can effectively improve the sensi-tivity and accuracy of malignant tumor diagnosis.It has high clinical application value and is worth vigorously promoting.

Breast tumorsNuclear magnetic resonanceMultimodal ultrasoundDiagnostic effectiveness

林洁、陈辉、褚爱鹏、陈红梅、成建华、李依明、黄文起

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476000 河南省商丘市第一人民医院

乳腺肿瘤 核磁共振 多模态超声 诊断效能

2024

实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
年,卷(期):2024.39(2)
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