Predictive Efficiency of Thinprep Cytologic Test,Ultrasound Elastography and Colposco-py on Precancerous Lesions of Cervical Cancer
Objective To explore the predictive efficiency of Thinprep cytologic test(TCT),ultrasound elastography and colposcopy on precancerous lesions of cervical cancer.Methods The data of 234 patients with precancerous lesions of cervical cancer who were treated in the hospital were reviewed.All patients received TCT,ultrasound elastography and colposcopy,and the cervical histopathological examination was used as the"gold standard"to analyze the predictive value of different detection meth-ods.Results Therewere207 cases(88.46%)of cervicalintraepithelialneoplasia(CIN)and27 cases(11.54%)of squamous cell carcinoma(SCC)among 234 patients with precancerous lesions of cervical cancer.There was a statistical significance in the positive detection rate of cervical lesions by different methods(P<0.05),and the positive detection rate was the highest by com-bination of TCT,ultrasound elastography and colposcopy and was and the lowest by TCT alone.There were statistical differences in the sensitivity,specificity,accuracy rate,positive predictive value and negative predictive value among different methods for pre-dicting the risk of precancerous lesions of cervical cancer(all P<0.05).The sensitivity was the highest in combination of the three,the specificity and positive predictive value were the highest in colposcopy,the accuracy rate and negative predictive value were the highest in ultrasound elastography combined with colposcopy,the sensitivity,accuracy rate,positive predictive value and negative detection value were the lowest in TCT,and the specificity was the lowest in TCT combined with colposcopy.Conclusion The combined detection of TCT,ultrasound elastography and colposcopy can improve the predictive efficiency on risk of of cervical precancerous lesions of CIN 2 and above,but it has no significant advantages over ultrasound elastography combined with colpos-copy.It is necessary to make comprehensive selection according to the actual situation in clinical practice.
Thinprep cytologic testUltrasound elastographyColposcopyPrecancerous lesions of cervical cancer
万方数据
维普
