Logistic Multivariate Analysis of Clinical Characteristics and Mortality in Patients with Malignant Tumors Combined with Coronary Heart Disease
Objective To explore the clinical characteristics and risk factors for death of patients with malignant tumors combined with coronary heart disease(CHD).Methods A retrospective analysis was conducted on the clinical data of 125 pa-tients with malignant tumors combined with CHD.They were divided into survival group and death group according to their clinical outcomes.A multivariate logistic regression model was used to analyze the risk factors for death in patients with malignant tumors combined with CHD.Results A total of 36 out of 125 malignant tumor patients with CHD died,with a mortality rate of 28.80%(36/125);Among 125 patients with malignant tumors and CHD,lymphoma accounted for42.40%(53/125),followed by gastric cancer[20.80%(26/125)],liver cancer[15.20%(19/125)],prostate cancer[10.40%(13/125)],and Cervical cancer[7.20%(9/125)];Univariate analysis showed that gender,age,body mass index(BMI),diabetes,peripheral vascular disease,antiplatelet or anticoagulant therapy were not related to the death of patients with malignant tumor combined with CHD(P>0.05);Chronic kidney disease,brain natriuretic peptide(BNP)and hemoglobin(Hb)were associated with the death of patients with malignant tumors complicated with CHD(P<0.05);Multifactor logistic regression analysis showed that there was chronic kidney disease(β =2.193,OR =8.960,95%CI =3.601～22.296),BNP≥568.8 pmol/L(β =2.388,OR =10.893,95%CI:4.071～29.143),Hb≤129.4 g/L(β =2.048,OR =7.751,95%CI =3.048～19.714)was an independent risk factor for mor-tality in patients with malignant tumors and CHD(P<0.05).Conclusion Lymphoma is the most common malignant tumor with CHD,and the risk of death is high,which is related to Chronic kidney disease,BNP≥568.8 pmol/L,Hb≤129.4 g/L.Clinically,we should attach great importance to the above risk factors,and take reasonable preventive measures in time to improve the surviv-al rate of patients as much as possible.
万方数据
维普
