首页|骨肉瘤软组织肿块骨化程度和临床病理特征分析

骨肉瘤软组织肿块骨化程度和临床病理特征分析

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目的 分析骨肉瘤软组织肿块(STM)骨化程度和临床病理特征.方法 回顾性分析136 例骨肉瘤患者的临床资料,采用X线对STM骨化程度进行评估,并分析骨化程度与患者临床病理特征的关系.结果 136 例骨肉瘤患者中,经X线检查显示无成骨型31 例,占比22.79%(31/136);部分成骨型82 例,占比60.29%(82/136);成骨型23 例,占比16.91%(23/136).病理形态分级为Ⅰ级29 例(21.32%),Ⅱ级 84 例(61.76%),Ⅲ级 23 例(16.91%);Enneking分期为ⅢB期患者的无成骨型占比 32.26%(10/31),明显高于部分成骨型 9.76%(8/82)和成骨型 8.70%(2/23)(P<0.05);无成骨型和部分成骨型化疗敏感度[58.06%(18/31)、59.76%(49/82)]明显高于成骨型[30.43%(7/23)](P<0.05).结论 骨肉瘤的STM骨化程度与Enneking分期及化疗敏感度存在明显关联性,临床可将患者病理特征作为手术和化疗治疗的参考依据.
Analysis of the Ossification Degree and Clinicopathological Characteristics of the Soft Tissue Mass in Osteosarcoma
Objective To analyze the ossification degree and clinicopathological features of a soft tissue mass(STM)in osteosarcoma.Methods Clinical data of 136 osteosarcoma patients were retrospectively analyzed,and STM was evaluated by X-ray,and the relationship with clinicopathological characteristics was analyzed.Results Of the 136 patients with osteosarcoma re-ceived X-ray examination,31 cases was non osteogenic type,22.79%(31/136),82 cases was partial osteogenic type,60.29%(82/136),23 cases was osteogenesis type,16.91%(23/136);The pathomorphological grade was grade Ⅰ in 29 patients,21.32%(29/136),Grade Ⅱ 84 cases,61.76%(84/136),Grade Ⅲ 23 cases,16.91%(23/136);Enneking stage,non osteogenic type was 32.26%(10/31),which was significantly higher than partial osteogenic type 9.76%(80.82)and osteogenic type 8.70%(2.23)(P<0.05);The chemotherapy sensitivity of non osteogenic and partial osteogenic type was 58.06%(18/31)and 59.76%(49/82),which were significantly higher than that of the osteogenic type by 30.43%(7/23)(P<0.05).Conclusion The obvious correlation between STM ossification and Enneking stage and chemotherapy sensitivity can provide a reference for sur-gery and chemotherapy treatment according to the pathological characteristics of patients.

Soft tissue of osteosarcomaDegree of ossificationLumpPathological features

王艳君、郑艳、刘新霞、肖晶晶、闫丹

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450000 郑州大学第一附属医院

骨肉瘤软组织 骨化程度 肿块 病理特征

2024

实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
年,卷(期):2024.39(3)
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