Objective To compare the effects of different ileal neobladder construction schemes after laparoscopic radi-cal cystectomy(RC)in patients with invasive bladder cancer.Methods The patients with myometrial invasive bladder cancer were prospectively included as the research objects,and were divided into 3 groups according to the random number table.All pa-tients underwent laparoscopic RC.In group A,orthotopic U-shaped ileal neobladder surgery was performed,in group B,orthotopic W-shaped ileal neobladder surgery was performed,and in group C,orthotopic ρ-shaped ileal neobladder surgery was performed.Univariate ANOVA was used to compare the operation conditions and urodynamic parameters 3 months after operation in the 3 groups,χ2 test was used to compare the recent postoperative complications in the 3 groups,Kruskal-Wallis H test and χ2 test were used to compare the recovery of urinary control function in the 3 groups.Results The operation time of group B was longer than that of group A and C,and the amount of bleeding during operation was more than that of group A and C,with a statistical signifi-cant difference(P<0.05).There was no statistical significant difference in the exhaust time and hospitalization time among the3 groups(P>0.05).There was no statistical significant difference in the total incidence of postoperative complications among the3 groups(P>0.05).Three months after operation,the maximum volume of new bladder in group B was the highest,followed by group A,and group C was the lowest,with statistically significant difference(P<0.05).There was no statistical significant differ-ence in maximum urinary flow rate,initial urinary bladder volume,new bladder compliance and residual urine volume among the 3 groups(P>0.05).The recovery time of urinary control function in group B was the shortest,followed by group C,and group A was the longest,with statistically significant difference(P<0.05).Conclusion Among the3 different new bladder construction schemes after laparoscopic RC surgery,the operation time of U-shaped and ρ-shaped new bladder is shorter,the operation time of W-shaped new bladder is the longest,and the amount of intraoperative bleeding is the largest,but the volume of new bladder after W-shaped surgery is the largest,the recovery time of urinary control function is the shortest,and the postoperative complications of the 3 construction schemes are less.