首页|浸润性膀胱癌患者腹腔镜根治性切除术后回肠新膀胱不同构建方案的效果对比

浸润性膀胱癌患者腹腔镜根治性切除术后回肠新膀胱不同构建方案的效果对比

Comparison of Different Ileal Neobladder Construction Schemes After Laparoscopic Radical Cystectomy in Patients with Invasive Bladder Cancer

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目的 对比腹腔镜根治性膀胱切除术(RC)后回肠新膀胱不同构建方案在浸润性膀胱癌患者中应用效果.方法 前瞻性纳入 124 例浸润性膀胱癌患者作为研究对象,按照随机数字表法分为 3 组.所有患者均行腹腔镜RC,A组行原位U形回肠新膀胱术,B组行原位W形回肠新膀胱术,C组行原位ρ形回肠新膀胱术.采用单因素方差分析比较3 组手术情况、术后3 个月尿流动力学参数,采用χ2 检验比较3 组术后近期并发症情况,采用Kruskal-Wallis H检验、χ2检验比较3 组患者术后尿控功能恢复情况.结果 B组手术时间较A组、C组长,术中出血量较A组、C组多,差异均有统计学意义(P<0.05);3 组排气时间、住院时间比较差异无统计学意义(P>0.05).3 组患者术后近期并发症总发生率比较,差异无统计学意义(P>0.05).术后3 个月,B组新膀胱最大容量最高,其次为A组,C组最低,差异有统计学意义(P<0.05);3 组间最大尿流率、初始尿意膀胱容量、新膀胱顺应性、残余尿量比较,差异无统计学意义(P>0.05).B组术后尿控功能恢复时间最短,其次为C组,A组最长,差异有统计学意义(P<0.05).结论 腹腔镜RC术后3 种不同新膀胱构建方案中U形、ρ形新膀胱手术时间较短,而W形新膀胱手术时间最长、术中出血量最多,但W形术后新膀胱容量最大,术后控尿功能恢复时间最短,3 种构建方案术后并发症均较少.
Objective To compare the effects of different ileal neobladder construction schemes after laparoscopic radi-cal cystectomy(RC)in patients with invasive bladder cancer.Methods The patients with myometrial invasive bladder cancer were prospectively included as the research objects,and were divided into 3 groups according to the random number table.All pa-tients underwent laparoscopic RC.In group A,orthotopic U-shaped ileal neobladder surgery was performed,in group B,orthotopic W-shaped ileal neobladder surgery was performed,and in group C,orthotopic ρ-shaped ileal neobladder surgery was performed.Univariate ANOVA was used to compare the operation conditions and urodynamic parameters 3 months after operation in the 3 groups,χ2 test was used to compare the recent postoperative complications in the 3 groups,Kruskal-Wallis H test and χ2 test were used to compare the recovery of urinary control function in the 3 groups.Results The operation time of group B was longer than that of group A and C,and the amount of bleeding during operation was more than that of group A and C,with a statistical signifi-cant difference(P<0.05).There was no statistical significant difference in the exhaust time and hospitalization time among the3 groups(P>0.05).There was no statistical significant difference in the total incidence of postoperative complications among the3 groups(P>0.05).Three months after operation,the maximum volume of new bladder in group B was the highest,followed by group A,and group C was the lowest,with statistically significant difference(P<0.05).There was no statistical significant differ-ence in maximum urinary flow rate,initial urinary bladder volume,new bladder compliance and residual urine volume among the 3 groups(P>0.05).The recovery time of urinary control function in group B was the shortest,followed by group C,and group A was the longest,with statistically significant difference(P<0.05).Conclusion Among the3 different new bladder construction schemes after laparoscopic RC surgery,the operation time of U-shaped and ρ-shaped new bladder is shorter,the operation time of W-shaped new bladder is the longest,and the amount of intraoperative bleeding is the largest,but the volume of new bladder after W-shaped surgery is the largest,the recovery time of urinary control function is the shortest,and the postoperative complications of the 3 construction schemes are less.

Bladder cancerLaparoscopic radical cystectomyIleal neobladderUrodynamics

关豪、熊建荣、朱要辉、郭灿琮

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467000 平煤神马医疗集团总医院

膀胱癌 腹腔镜根治性膀胱切除术 回肠新膀胱术 尿流动力学

2024

实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
年,卷(期):2024.39(3)
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