Analysis of Influencing Factors on Long-term Prognosis of Patients with Glioma After Operation
Objective To explore the factors related to the long-term prognosis of patients with brain glioma after surger-y.Methods 94 patients with glioma were selected and their general data were analyzed to evaluate the influencing factors of long-term prognosis of glioma patients after surgery.Results The patients were followed up for 3 months to 5 years,The 1-,2-,3-,4-and 5-year survival rates of 94 patients were 79.79%(75/94),58.51%(55/94),40.43%(38/94),30.85%(29/94),and22.34%(21/94),respectively.The median survival time was29 months;The percentage of pathological grade Ⅳ,preopera-tive KPS score＜70,tumor size≥6 cm,partial resection,no combination of radiotherapy and chemotherapy,no seizure before op-eration and peritumoral edema in poor prognosis group was higher than that in good prognosis group(P＜0.05).Multivariate re-gression analysis showed that pathological grade,preoperative KPS score,tumor size,resection degree,combination of radiotherapy and chemotherapy,preoperative seizure and peritumoral edema were the influencing factors for the long-term prognosis of patients with glioma after operation(P＜0.05).Conclusion Pathological grading,preoperative KPS score,tumor size,degree of resec-tion,combination of radiotherapy and chemotherapy,preoperative epileptic seizures,and peritumoral edema are the long-term prog-nostic factors for patients with glioma.Reasonable measures should be taken actively to improve the surgical treatment effect and disease prognosis.
Brain gliomaPrognosisPathological gradingTumor sizeDegree of excisionPeritumoral edemaInfluence factor
万方数据
维普
