Prognostic Analysis of Different Cervical Lymph Node Metastasis Transitions in T1 Stage Nasopharyngeal Carcinoma Patients During Precise Radiotherapy
Objective To investigate the prognosis of nasopharyngeal carcinoma(NPC)patients with T1 stage and differ-ent cervical lymph node metastasis states during precise radiotherapy.Methods 86 locally early NPC patients(T1N0-3M0-1 stage)who underwent simple radiotherapy or chemotherapy were selected as the study subjects.All patients were followed up for 3 years after treatment.Kaplan Meier analysis was used to investigate the survival prognosis of NPC patients in T1 stage with differ-ent cervical lymph node metastasis states.Results The overall 3-year survival rate of 86 patients was 90.70%(78/86),of which 27 patients with T1N0M0 stage survived,with a survival rate of 100%(27/27);A total of 32 T1N1M0 patients survived,with a survival rate of 91.43%(32/35);A total of 9 T1N2M0 patients survived,with a survival rate of 90.00%(9/10);A total of 6 T1N3M0 patients survived,with a survival rate of 75.00%(6/8);A total of 4 T1N0-3M1 patients survived,with a survival rate of 66.67%(4/6).Among T1 stage NPC patients with different N stages who underwent simple radiotherapy or radiochemotherapy,a total of 13 cases failed treatment,of which5 cases had simple recurrence,accounting for38.46%(5/13);There were6 cases of simple metastasis,accounting for46.15%(6/13);There were 2 cases of recurrence and metastasis,accounting for 15.38%(2/13).A total of 18 out of 86 patients experienced adverse reactions,with dry mouth accounting for 33.33%(6/18),followed by 4 cases of dental discomfort(22.22%),3 cases of auditory damage(16.67%),3 cases of auditory abnormalities(16.67%),1 case of taste abnormalities(5.56%),and 1 case of neck stiffness(5.56%).Conclusion T1 stage NPC patients have a higher rate of cervical lymph node metastasis,but radiotherapy is effective in controlling the condition.The long-term adverse reactions of precise radiotherapy techniques have no significant impact on the quality of life of patients.
万方数据
维普
