Effect Analysis of Hemilateral Osteocortical Resection and Inactivated Replantation in Low-degree Malignant Bone Tumors of the Limbs
Objective To discuss the efficacy of inactivated replantation in low-degree malignant bone tumors of the limbs.Methods 108 cases of low-degree malignant bone tumors in the limbs were selected.The control group(n =54)and the study group(n =54)were divided according to the randomized digital table.The control group used artificial joint replacement,and the study group used hemiosteocortical resection and inactivated regrafting.Comparison of excellent rate,perioperative chan-ges,daily life function,limb ability,serum factors[tumor necrosis factor-(TNF-),soluble vascular adhesion molecule(s VCAM-1)],and complication incidence changes.Results The excellent rate was 96.30%(52/54)than 72.22%(39/54)(P<0.05);In comparison with the control group,The duration of surgery and the length of hospitalization in the study group,And less intraoperative bleeding(P<0.05);In comparison with the control group,High daily life function and limb ability scores in the study group at 6 months after surgery(P<0.05);In comparison with the control group,The levels of TNF-and s VCAM-1 were low in the study group at 6 months after surgery(P<0.05);The incidence of amputation and muscle atrophy in the study group was 1.85%(1/54),7.41%(4/54)and 5,5.56%(3/54)and 14.81%(8/54)(P>0.05),The incidence of infection of 0.00%(0/54)was lower than 16.67%(9/54)in the control group(P<0.05).Conclusion Reactivationandreplantationin low malignant bone tumors can improve the excellent rate,improve perioperative changes,downregulate serum factors,improve dai-ly life function and limb ability,and reduce the risk of postoperative infection.
Low-grade malignant bone tumors of limbsHemiosteocortical resectionImmune capacitySerum tumor markers
万方数据
维普
