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膀胱癌患者根治术后合并前列腺偶发癌的临床病理特征分析

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目的 分析膀胱癌患者根治术后合并前列腺偶发癌的临床病理特征.方法 回顾性分析行膀胱癌根治术75例患者的临床资料,所有患者术前均未被诊断为前列腺癌,统计术后前列腺偶发癌的发生率.另收集患者的年龄、膀胱癌分期等资料,统计对比合并前列腺偶发癌与未合并前列腺偶发癌患者各项临床资料的差异;同时统计分析合并前列腺偶发癌患者的病理特点;于术后进行随访,统计所有患者的生存率.结果 75例患者中,合并前列腺偶发癌的共有18例,发生率为24.00%(18/75);合并前列腺偶发癌的患者年龄高于未合并前列腺偶发癌患者,有统计学差异(P<0.05);而两组术前的国际前列腺症状评分(IPSS)、生活质量综合评定问卷(GQOLI-74)、前列腺特异抗原(PS A)相比,无统计学差异(P>0.05);18例合并前列腺偶发癌的患者其临床分期大部分局限于pT2内,其中pT,有10例(55.56%),pT2有5例(27.78%),pT3有3例(16.67%);采用Gleason score评分对患者评估,其中<7分11例(61.11%)、=7分5例(27.78%)、>7分2例(11.11%);术后随访成功60例,生存率为80.00%(60/75),其中11例死于膀胱癌,4例死于其他疾病.结论 膀胱癌根治术后前列腺偶发癌的发生率较高,大多局限于pT2内,且Gleason score评分多数≤7分,前列腺偶发癌的发生对膀胱癌患者总体生存率无显著影响.
Clinical Characteristics of Incidental Prostate Cancer After Radical Resection of Bladder Cancer
Objective To analyze the clinical characteristics of incidental prostate cancer after radical resection of blad-der cancer.Methods The clinical data of 75 patients with bladder cancer who underwent radical resection were retrospectively analyzed.All patients were not diagnosed as prostate cancer before operation.In addition,the age and stage of bladder cancer were collected,and the differences of clinical data between patients with incidental prostate cancer and those without incidental prostate cancer were statistically compared;Simultaneously statistically analyze the pathological characteristics of patients with incidental prostate cancer;Follow up after surgery and calculate the survival rate of all patients.Results Among the 75 patients,there were 18 cases of incidental prostate cancer,with an incidence rate of 24.00%(18/75);The age of patients with concomitant prostate cancer was higher than that of patients without concomitant prostate cancer,with a statistical difference(P<0.05);However,there was no statistically significant difference(P>0.05)in the preoperative International Prostate Symptom Scale(IPSS),Com-prehensive Quality of Life Questionnaire(GQOLI-74),and Prostate Specific Antigen(PSA)between the two groups;The clinical staging of 18 patients with incidental prostate cancer was mostly limited to pT2,with 10 cases(55.56%)of pT1,5 cases(27.78%)of pT2,and 3 cases(16.67%)of pT3;The Gleason score was used to evaluate patients,with 11 cases(61.11%)having a score of<7,5 cases(27.78%)having a score of=7,and 2 cases(11.11%)having a score of>7;60 cases were fol-lowed up successfully,the survival rate was 80.00%(60/75),11 cases died of bladder cancer,4 cases died of other diseases.Conclusion Incidental prostate cancer after radical resection of bladder cancer has a high incidence,mostly confined to pT2,and Gleason score is mostly ≤7.Incidental prostate cancer has no significant impact on the overall survival rate of patients with blad-der cancer.

Bladder cancerIncidental prostate cancerClinical pathological characteristicsSurvival rate

王阳、李新悟、段启新、李征、胡跃世、谷傲峥、朱清

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473000 河南省南阳市中心医院

膀胱癌 前列腺偶发癌 临床病理特征 生存率

2024

实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
年,卷(期):2024.39(5)
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