首页|超声引导下射频消融与外科手术治疗低风险甲状腺微小乳头状癌患者的疗效比较

超声引导下射频消融与外科手术治疗低风险甲状腺微小乳头状癌患者的疗效比较

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目的 比较低风险甲状腺微小乳头状癌患者应用超声引导下射频消融与外科手术治疗的疗效.方法 回顾分析205例甲状腺微小乳头状癌患者的临床资料.按手术方式将其分为外科组(n=91,采用外科手术治疗)和射频消融组(n=114,采用超声引导下射频消融治疗),对比两组围术期指标,术后随访24个月,比较两组手术前及术后1个月的甲状腺功能,对比两组预后,比较两组并发症发生率.结果 射频消融组与外科组相比较,围术期各指标均更低,差异有统计学意义(P<0.05),术后1个月相较于术前,射频消融组TG、TGAb差异无统计学意义(P>0.05),外科组TG、TGAb高于术前,差异有统计学意义(P<0.05).射频消融组TG、TGAb低于外科组,差异有统计学意义(P<0.05).射频消融组与外科组相互比较,术后24个月内肿瘤复发率、淋巴结转移率差异无统计学意义(P>0.05),并发症总发生率更低,差异有统计学意义(P<0.05).结论 应用超声引导下射频消融治疗低风险甲状腺微小乳头状癌患者疗效尚可,可加速患者康复进程,减少术中对甲状腺功能的损伤,降低并发症发生风险.
Comparison of Ultrasound-guided Radiofrequency Ablation and Surgical Procedure in Treating Patients with Low-risk Thyroid Micropapillary Carcinoma
Objective To compare the efficacy of ultrasound-guided radiofrequency ablation and surgical procedure in patients with low-risk thyroid micropapillary carcinoma.Methods The clinical data of 205 patients with thyroid micropapillary carcinoma were retrospectively analyzed.The patients were divided into surgical group(n=91,surgical procedure)and radiofre-quency ablation group(n=114,ultrasound-guided radiofrequency ablation)according to surgical methods.Perioperative indicators were compared between the 2 groups.The patients were followed up for 24 hours after surgery,and the thyroid function before sur-gery and at 1 month after surgery,prognosis and incidence rates of complications were compared between the 2 groups.Results Compared with surgical group,the perioperative indicators in radiofrequency ablation group were lower(P<0.05).At 1 month af-ter surgery,the levels of TG and TGAb in radiofrequency ablation group had no statistically significant differences compared with those before surgery(P>0.05),but the levels of TG and TGAb in surgical group were higher than those before surgery(P<0.05).TG and TGAb in radiofrequency ablation group were lower than those in surgical group(P<0.05).There were no statisti-cal differences in tumor recurrence rate and lymph node metastasis rate within 24 months after surgery between radiofrequency ab-lation group and surgical group(P>0.05),and the total incidence rate of complications was lower in radiofrequency ablation group(P<0.05).Conclusion The efficacy of ultrasound-guided radiofrequency ablation is acceptable in the treatment of pa-tients with low-risk thyroid micropapillary carcinoma,which can accelerate the rehabilitation process,reduce the intraoperative in-jury to thyroid function and lower the risk of complications.

Low-risk thyroid micropapillary carcinomaUltrasound-guided radiofrequency ablationSurgical procedure

付伟娟、江艳丽、胡举

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471000 河南科技大学第二附属医院

低风险甲状腺微小乳头状癌 超声引导下射频消融 外科手术

2024

实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
年,卷(期):2024.39(6)