首页|超声引导下双侧闭孔神经阻滞联合咪达唑仑静脉麻醉对膀胱癌手术患者血流动力学及苏醒质量的影响

超声引导下双侧闭孔神经阻滞联合咪达唑仑静脉麻醉对膀胱癌手术患者血流动力学及苏醒质量的影响

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目的 探讨超声引导下双侧闭孔神经阻滞联合咪达唑仑静脉麻醉对膀胱癌手术患者血流动力学及苏醒质量的影响.方法 选取拟行手术治疗的98例膀胱癌患者进行前瞻性随机对照研究,通过随机数字表法将其分为对照组和研究组,各49例.对照组给予咪达唑仑静脉全麻,观察组在对照组基础上联用超声引导下双侧闭孔神经阻滞.对比两组麻醉前(T1)、麻醉后20 min(T2)、麻醉后40 min(T3)、术后拔管时(T4)血流动力学[心率(HR)、平均动脉压(MAP)]、苏醒质量[Steward苏醒评分、意识状态OAAS评分(OAAS)]及咪达唑仑使用剂量.结果 随着T1、T2、T3、T4时点推移,两组HR、MAP水平均下降,且观察组T2、T3、T4时点HR、MAP水平均高于对照组(P<0.05).观察组Steward苏醒评分、OAAS评分显著高于对照组(P<0.05).对照组咪达唑仑剂量为5~10 mg,平均(7.64±1.23)mg;观察组咪达唑仑剂量为5~8 mg,平均(6.65±0.55)mg.观察组咪达唑仑剂量显著少于对照组,差异有统计学意义(t=5.143,P<0.001).结论 超声引导下双侧闭孔神经阻滞联合咪达唑仑静脉麻醉可提高膀胱癌手术患者苏醒质量,且对血流动力学影响较小,麻醉效果好.
Effects of Ultrasound Guided Bilateral Obturator Nerve Block Combined with Midazolam Intravenous Anesthesia on Hemodynamics and Recovery Quality of Patients Underwent Bladder Cancer Surgery
Objective To investigate the effect of ultrasound guided bilateral obturator nerve block combined with mid-azolam intravenous anesthesia on hemodynamics and recovery quality of patients undergoing bladder cancer surgery.Methods A prospective randomized controlled study was conducted on 98 patients with bladder cancer who were admitted to the hospital for surgical treatment.They were divided into the control group and the study group by random number table,with 49 cases in each group.The control group was given midazolam intravenous anesthesia,and the observation group was given ultrasound guided bilat-eral obturator nerve block on the basis of the control group.The hemodynamics[heart rate(HR),Mean arterial pressure(MAP)],recovery quality[Steward recovery score,OAAS score for state of consciousness(OAAS)]and the dosage of midazo-lam were compared before anesthesia(T1),20 minutes after anesthesia(T2),40 minutes after anesthesia(T3),and at the time of extubation(T4)after surgery between the two groups.Results With the passage of time points T1,T2,T3,and T4,the levels of HR and MAP in both groups decreased,and the HR and MAP levels in the observation group at time points T2,T3,and T4 were higher than those in the control group(P<0.05).The Steward awakening score and OAAS score in the observation group were significantly higher than those in the control group(P<0.05).In the control group,the dose of midazolam was 5~10 mg,with an average of(7.64±1.23)mg.The dose of midazolam in the observation group was 5~8 mg,with an average of(6.65±0.55)mg.The dose of midazolam in the observation group was significantly lower than that in the control group(t=5.143,P<0.001).Conclusion Ultrasound guided bilateral obturator nerve block combined with midazolam intravenous anesthesia can improve the quality of recovery of patients undergoing bladder cancer surgery,and has little impact on hemodynamics,with good anesthetic effect.

Bladder cancerUltrasound guided bilateral obturator nerve blockMidazolamAwakening qualityHemody-namics

司马靓杰、苗亚飞、麻黎斯、刘稳、司建洛

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471003 河南科技大学临床医学院,河南科技大学第一附属医院

膀胱癌 超声引导下双侧闭孔神经阻滞 咪达唑仑 苏醒质量 血流动力学

2024

实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
年,卷(期):2024.39(6)