Objective To compare and analyze the efficacy of lobectomy and segmentectomy in patients with early non-small cell lung cancer(NSCLC)with a diameter of ≤2 cm.Methods 80 early NSCLC patients with a diameter ≤2 cm were se-lected and randomly divided into the control group(40 cases)and the observation group(40 cases)using a random number table method.The control group underwent lobectomy,while the observation group underwent segmentectomy,with follow-up up to 1 year after surgery.Compare the 2 groups of surgical related indicators,lung ventilation function indicators,immune function,com-plications,and 1-year survival rate.Results The intraoperative blood loss in the observation group was(72.31±8.29)ml,and the postoperative drainage volume was(437.89±26.31)ml,which was lower than the control group's(98.75±10.63)ml and(512.75±30.58)ml,with a surgical time of(139.46±9.75)minutes,longer than the control group's(113.68±8.21)minutes,and a hospital stay of(7.26±1.59)days,shorter than the control group's(9.83±2.31)days,with statistical differences(P＜0.05);After surgery,the observation group had a forced vital capacity(FV C)of(2.10±0.51)L,a forced respiratory volume(FEV1)of(1.29±0.23)L at the first second,peak expiratory flow(PEF)L/s of(3.88±0.42),CD3+of(42.75±5.38)％,and CD4+of(36.35±4.69)％,all of which were higher than those of the control group[(1.63±0.40)L,(0.91±0.20)L,(3.21±0.30)L/s,(36.31±4.26)％,(31.26±4.15)％].The observation group had a CD8+of(24.3±0.40)L,(0.91±0.20)L,(3.21±0.30)Us 20±3.05％,(29.53±3.41)％lower than the control group,with a statistically significant differ-ence(P＜0.05);There was no statistically significant difference in the incidence of complications and 1-year survival between the 2 groups(P＞0.05).Conclusion Lobectomy and segmentectomy have significant effects on the treatment of early NSCLC pa-tients with a diameter ≤2 cm,and both can achieve excellent mid to long term prognosis.However,segmentectomy has less intrao-perative bleeding and postoperative drainage volume,shorter hospital stay,less impact on lung ventilation and immune function,and no serious complications.
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